2-(2,2,2-Trifluoroethylamino)-5-chlorobenzophenone

Base Information

• Chemical Name: 2-(2,2,2-Trifluoroethylamino)-5-chlorobenzophenone
• CAS No.: 22753-80-6
• Molecular Formula: C15H11 Cl F3 N O
• Molecular Weight: 313.707
• Hs Code.: 2922399090
• European Community (EC) Number: 245-199-7
• UNII: S7672FVH7C
• DSSTox Substance ID: DTXSID40177301
• Nikkaji Number: J286.295F
• Wikidata: Q83047624
• Mol file: 22753-80-6.mol

Synonyms:22753-80-6;2-(2,2,2-Trifluoroethylamino)-5-chlorobenzophenone;EINECS 245-199-7;[5-chloro-2-(2,2,2-trifluoroethylamino)phenyl]-phenylmethanone;5-Chloro-2-((2,2,2-trifluoroethyl)amino)benzophenone;S7672FVH7C;5-CHLORO-2-[(2,2,2-TRIFLUOROETHYL)AMINO]BENZOPHENONE;Methanone, (5-chloro-2-((2,2,2-trifluoroethyl)amino)phenyl)phenyl-;2-[N-(2,2,2-Trifluoroethyl)amino]-5-chlorobenzophenone;2-(N-(2,2,2-TRIFLUOROETHYL)AMINO)-5-CHLOROBENZOPHENONE;C15H11ClF3NO;UNII-S7672FVH7C;5-Chloro-2-[amino]benzophenone;SCHEMBL11293404;DTXSID40177301;C15-H11-Cl-F3-N-O;5-chloro-2-(2,2,2-trifluoroethylamino)benzophenone;5-Cloro-2-[(2,2,2-trifluoroethyl)amino]benzophenone;[5-Chloro-2-[(2,2,2-trifluoroethyl)amino]phenyl]phenyl ketone;2-(N-(2,2,2-TRIFLUOROETHYL)AMINO)-5-CHLOROBENZOPHENONE [USP-RS]

Chemical Property of 2-(2,2,2-Trifluoroethylamino)-5-chlorobenzophenone

Chemical Property:

• Vapor Pressure: 8.94E-08mmHg at 25°C
• Melting Point: 99-100 °C
• Boiling Point: 435.2°Cat760mmHg
• PKA: -1.38±0.50(Predicted)
• Flash Point: 217°C
• PSA: 29.10000
• Density: 1.353g/cm³
• LogP: 4.61820
• XLogP3: 5.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 313.0481262
• Heavy Atom Count: 21
• Complexity: 355

Purity/Quality:

99% ^*data from raw suppliers

2-(2,2,2-Trifluoroethylamino)-5-chlorobenzophenone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)C2=C(C=CC(=C2)Cl)NCC(F)(F)F
• Uses: 2-(2,2,2-Trifluoroethylamino)-5-chlorobenzophenone is a benzophenone derivative with the potential to act as a photo-initiator in applications involving the prevention of UV light damage on polymer films.

Technology Process of 2-(2,2,2-Trifluoroethylamino)-5-chlorobenzophenone

There total 2 articles about 2-(2,2,2-Trifluoroethylamino)-5-chlorobenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2,2-trifluoroethyltrichloromethanesulfonate (23199-56-6) + 5-chloro-2-aminobenzophenone (719-59-5) → 5-chloro-2-[(2,2,2-trifluoroethyl)amino]benzophenone (22753-80-6)

Guidance literature:

DOI:10.1021/jm00270a008

Reference yield:

→ 5-chloro-2-[(2,2,2-trifluoroethyl)amino]benzophenone (22753-80-6)

Guidance literature:

/BRN= 475640/, NaH, F3C-CH2-Br;

Reference yield:

2-Bromoacetyl bromide (598-21-0) + 5-chloro-2-[(2,2,2-trifluoroethyl)amino]benzophenone (22753-80-6) → N-(2-benzoyl-4-chlorophenyl)-2-bromo-N-(2,2,2-trifluoroethyl)acetamide (22753-81-7)

Guidance literature:

DOI:10.1021/jm00270a008

upstream raw materials:

2,2,2-trifluoroethyltrichloromethanesulfonate

5-chloro-2-aminobenzophenone

Downstream raw materials:

N-(2-benzoyl-4-chlorophenyl)-2-bromo-N-(2,2,2-trifluoroethyl)acetamide

halazeapam

1-(2,2,2-Trifluoroethyl)-4-phenyl-6-chloro-2(1H)-quinazolinone

Refernces