1-Pyrenemethanol

Base Information

• Chemical Name: 1-Pyrenemethanol
• CAS No.: 24463-15-8
• Molecular Formula: C17H12 O
• Molecular Weight: 232.282
• Hs Code.: 2906299090
• UNII: C76UX3EH8M
• DSSTox Substance ID: DTXSID90179219
• Nikkaji Number: J346.057F
• Wikidata: Q63409878
• ChEMBL ID: CHEMBL1743299
• Mol file: 24463-15-8.mol

Synonyms:1-hydroxymethyl-pyren;1-hydroxymethylpyrene;1-pyrenemethanol;pyrenemethanol

Chemical Property of 1-Pyrenemethanol

Chemical Property:

• Appearance/Colour: Yellow Solid
• Vapor Pressure: 4.46E-09mmHg at 25°C
• Melting Point: 123-126oC(lit.)
• Boiling Point: 455.2°Cat760mmHg
• PKA: 14.36±0.10(Predicted)
• Flash Point: 207.5°C
• PSA: 20.23000
• Density: 1.321g/cm³
• LogP: 4.07630
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 232.088815002
• Heavy Atom Count: 18
• Complexity: 313

Purity/Quality:

98%, ^*data from raw suppliers

1-Pyrenemethanol ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC2=C3C(=C1)C=CC4=C(C=CC(=C43)C=C2)CO
• Uses: 1-Pyrenemethanol (cas# 24463-15-8) is a compound useful in organic synthesis. 1-Pyrenemethanol can be used:For the synthesis of pincer-like benzene-bridged fluorescent selective sensor for adenosine-5′-triphosphate (ATP) detection.As a starting material for the synthesis of pyrene-end poly(glycidyl methacrylate) polymer.As an initiator for the synthesis of pyrene core star polymers.For the synthesis of 1-pyrenecarboxaldehyde, an important intermediate in pharmaceutical and agrochemical fields.

Technology Process of 1-Pyrenemethanol

There total 10 articles about 1-Pyrenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.4%

1-(pyren-1-ylmethyloxy)-2-pyridone (220196-58-7) → 2-Pyridone (142-08-5,1199357-22-6) + 1-Hydroxy-2-pyridon (822-89-9) + 1-pyrenemethanol (24463-15-8) + methyl 1-pyrenylmethyl ether (91385-15-8)

Guidance literature:

In methanol; Ambient temperature; Irradiation;

DOI:10.1016/S0040-4039(98)02282-5

Reference yield: 17.3%

1-(pyren-1-ylmethyloxy)-2-pyridone (220196-58-7) → pyrene-1-aldehyde (3029-19-4) + 1-pyrenemethanol (24463-15-8) + methyl 1-pyrenylmethyl ether (91385-15-8)

Guidance literature:

In methanol; Ambient temperature; Irradiation;

DOI:10.1016/S0040-4039(98)02282-5

Reference yield: 3.0%

1-(pyren-1-ylmethyloxy)-2-pyridone (220196-58-7) → 2-Pyridone (142-08-5,1199357-22-6) + 1-Hydroxy-2-pyridon (822-89-9) + pyrene-1-aldehyde (3029-19-4) + 1-pyrenemethanol (24463-15-8)

Guidance literature:

In methanol; Ambient temperature; Irradiation;

DOI:10.1016/S0040-4039(98)02282-5

upstream raw materials:

1-pyrenylmethyl p-toluate

(1-pyrenyl)methoxycarbonylglycine

1-(pyren-1-ylmethyloxy)-2-pyridone

1,2,3,4-di-O-isopropylidene-D-galactopyranosyl pyren-1-ylmethoxycarbonate

Downstream raw materials:

1-chloromethylpyrene

4-nitrophenyl (pyren-1-ylmethyl)carbonate

1-(azidomethyl)pyrene

pyrene-1-aldehyde

Refernces

• 1、 Chen, Wei,Bay, Wan Ping,Wong, Ming Wah,Huang, Dejian. "Selenium Blue-α and -β: Turning on the fluorescence of a pyrenyl fluorophore via oxidative cleavage of the Se-C bond by reactive oxygen species". supporting information; scheme or table. p. 3843 - 3846. Retrieved 2012/08/13.
• 2、 Yoshioka, Nariyoshi,Andoh, Chihei,Kubo, Kanji,Igarashi, Tetsutaro,Sakurai, Tadamitsu. "Competitive occurrence of homolytic N-O and heterolytic C-O bond cleavage in excited-state 1-(arylmethyloxy)-2-pyridones". . p. 1927 - 1932. Retrieved 2007/10/03.