diethyl (2,5-dimethylphenyl)phosphoramidate

Base Information

• Chemical Name: diethyl (2,5-dimethylphenyl)phosphoramidate
• CAS No.: 22846-97-5
• Molecular Formula: C₁₂H₂₀NO₃P
• Molecular Weight: 257.269
• Mol file: 22846-97-5.mol

Synonyms:NSC263537

Chemical Property of diethyl (2,5-dimethylphenyl)phosphoramidate

Chemical Property:

• Vapor Pressure: 0.000375mmHg at 25°C
• Boiling Point: 317.9°Cat760mmHg
• Flash Point: 146°C
• Density: 1.129g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of diethyl (2,5-dimethylphenyl)phosphoramidate

There total 2 articles about diethyl (2,5-dimethylphenyl)phosphoramidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

mononitro-p-xylene (89-58-7) + triethyl phosphite (122-52-1) → (2,5-Dimethyl-phenyl)-phosphoramidic acid diethyl ester (22846-97-5)

Guidance literature:

In toluene; at 200 ℃; for 0.25h; under 15001.5 Torr; Microwave irradiation;

DOI:10.1016/j.tetlet.2009.09.037

Reference yield:

Diethyl phosphonate (762-04-9,123-22-8) + 2,5-Dimethylaniline (95-78-3) → (2,5-Dimethyl-phenyl)-phosphoramidic acid diethyl ester (22846-97-5)

Guidance literature:

With triethylamine; In tetrachloromethane;

DOI:10.1021/ja01031a024

upstream raw materials:

Diethyl phosphonate

2,5-Dimethylaniline

mononitro-p-xylene

triethyl phosphite

Refernces