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2-[(2-phenylacetyl)-propyl-amino]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide

Base Information Edit
  • Chemical Name:2-[(2-phenylacetyl)-propyl-amino]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
  • CAS No.:5908-40-7
  • Molecular Formula:C22H23N3O2S
  • Molecular Weight:130.262
  • Hs Code.:2931900090
  • DSSTox Substance ID:DTXSID10360001
  • Wikidata:Q82141484
  • Mol file:5908-40-7.mol
2-[(2-phenylacetyl)-propyl-amino]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide

Synonyms:5908-40-7;2-[(2-phenylacetyl)-propyl-amino]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide;DTXSID10360001

Suppliers and Price of 2-[(2-phenylacetyl)-propyl-amino]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
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Chemical Property of 2-[(2-phenylacetyl)-propyl-amino]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide Edit
Chemical Property:
  • Boiling Point:°Cat760mmHg 
  • Flash Point:°C 
  • PSA:94.03000 
  • Density:1.236g/cm3 
  • LogP:4.87940 
  • XLogP3:4.1
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:8
  • Exact Mass:393.15109816
  • Heavy Atom Count:28
  • Complexity:504
Purity/Quality:
Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Canonical SMILES:CCCN(CC(=O)NC1=NC(=CS1)C2=CC=CC=C2)C(=O)CC3=CC=CC=C3
  • Physical properties Clear liquid; bp 74 °C/96 mmHg; d 0.8274 g cm?3 (26 °C), n26/D 1.4188.
  • Uses Trimethylsilylacetone reacts with Grignard or organolithium reagents to provide, after elimination, 2-substituted 2-propenes; in combination with fluoride ion, gives chemistry of the corresponding enolate ion; can direct electrophilic substitution to either side of the carbonyl group, participating in (but not limited to) reactions: Preparation of 2-substituted α-Alkenes, Reaction with Electrophiles, Reaction with Fluoride Ion, Reaction with Strong Bases, etc.
Technology Process of 2-[(2-phenylacetyl)-propyl-amino]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide

There total 9 articles about 2-[(2-phenylacetyl)-propyl-amino]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With copper(l) iodide; In diethyl ether; at -78 - 20 ℃;
DOI:10.1021/jo00275a004
Guidance literature:
With (CH3CO)2O; In not given; CH3SiCH2MgBr and (CH3CO)2O; hydrolysis;;
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