3-Methoxyestra-2,5(10)-dien-17beta-ol

Base Information Edit

Chemical Name:3-Methoxyestra-2,5(10)-dien-17beta-ol
CAS No.:1091-93-6
Molecular Formula:C19H28 O2
Molecular Weight:288.43
Hs Code.:
European Community (EC) Number:214-130-2
NSC Number:67575
UNII:UC5Y491C32
DSSTox Substance ID:DTXSID60148816
Nikkaji Number:J217.209G
Wikidata:Q27116001
Mol file:1091-93-6.mol

Synonyms:1091-93-6;3-Methoxyestra-2,5(10)-dien-17beta-ol;1,4-Dihydroestradiol 3-methyl ether;UNII-UC5Y491C32;3-Methoxyestra-2,5(10)-diene-17beta-ol;(8R,9S,13S,14S,17S)-3-methoxy-13-methyl-1,4,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-ol;UC5Y491C32;EINECS 214-130-2;NSC-67575;EC 214-130-2;3-Methoxyestra-2,5(10)-dien-17-ol;SCHEMBL7956765;CHEBI:34341;DTXSID60148816;NSC67575;NSC 67575;3-methoxyestra-2,5(10)-dien-17b-ol;3-methoxy-2,5(10)-estradien-17beta-ol;3-Methoxy-estra-2,5(10)-dien-17beta-ol;1,4-DIHYDRO-3,17-ESTRADIOL 3-METHYL ETHER;W-109634;3-METHOXYESTRA-2,5(10)-DIEN-17.BETA.-OL;3-METHYLOXYESTR-2,5(10)-DIEN-17.BETA.-OL;Q27116001;3-METHOXY-19-NORANDROSTA-2(3),5(10)-DIEN-17.BETA.-OL;ESTRA-2,5(10)-DIEN-17-OL, 3-METHOXY-, (17.BETA.)-ESTRA-2,5(10)-DIEN-17.BETA.-OL, 3-METHOXY-

Suppliers and Price of 3-Methoxyestra-2,5(10)-dien-17beta-ol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 15 raw suppliers

Chemical Property of 3-Methoxyestra-2,5(10)-dien-17beta-ol Edit

Chemical Property:

Vapor Pressure:0.001Pa at 25℃
Boiling Point:437.1°Cat760mmHg
Flash Point:192.3°C
PSA：29.46000
Density:1.11g/cm³
LogP:4.20430
Water Solubility.:5mg/L at 25℃
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:288.208930132
Heavy Atom Count:21
Complexity:504

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2O)CCC4=C3CC=C(C4)OC
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3CC=C(C4)OC
Uses 3-Methoxyestra-2,5(10)-diene-17β-ol has been shown to up regulate estrogen receptor (ER), ER-α and ER-β in a time-dependent manner which significantly increases mRNA expression and time-dependently decreases ER-β/ER-α ratio in skin fibroblasts in postmenopausal women.

Technology Process of 3-Methoxyestra-2,5(10)-dien-17beta-ol

There total 21 articles about 3-Methoxyestra-2,5(10)-dien-17beta-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1624-62-0
estrone 3-methyl ether

: 1091-93-6
3-methoxy-17-hydroxyestra-2,5⁽¹⁰⁾-diene

Guidance literature:: With N,N'-Dimethylurea; tris(pyrrolidino)phosphine oxide; lithium bromide; In tetrahydrofuran; Electrochemical reaction;
DOI:10.1126/science.aav5606