2-Methyladenine

Base Information

• Chemical Name: 2-Methyladenine
• CAS No.: 1445-08-5
• Deprecated CAS: 936-23-2
• Molecular Formula: C6H7 N5
• Molecular Weight: 149.155
• Hs Code.: 2933990090
• NSC Number: 26364
• DSSTox Substance ID: DTXSID80162731
• Nikkaji Number: J80.113E
• Wikidata: Q15632702
• ChEMBL ID: CHEMBL330897
• Mol file: 1445-08-5.mol

Synonyms:2-methyladenine

Chemical Property of 2-Methyladenine

Chemical Property:

• Vapor Pressure: 0.00191mmHg at 25°C
• Refractive Index: 1.858
• Boiling Point: 369.1°Cat760mmHg
• Flash Point: 204.7°C
• PSA: 80.48000
• Density: 1.49g/cm³
• LogP: 0.82470
• Storage Temp.: 2-8°C(protect from light)
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 149.07014524
• Heavy Atom Count: 11
• Complexity: 150

Purity/Quality:

99%+, ^*data from raw suppliers

2-methyl-9H-purin-6-amine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NC(=C2C(=N1)N=CN2)N

Technology Process of 2-Methyladenine

There total 12 articles about 2-Methyladenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,6-diamino-5-nitroso-2-methylpyrimidine (56472-03-8) → 2-methyl-6-aminopurine (1445-08-5)

Guidance literature:

With formic acid; sodium dithionite; formamide;

DOI:10.1021/ja01563a078 DOI:10.1021/ja01519a043

Reference yield:

→ 2-methyl-6-aminopurine (1445-08-5)

Guidance literature:

With formamide;

DOI:10.1021/ja01098a003

Reference yield:

N-(4,6-diamino-2-methyl-pyrimidin-5-yl)-formamide → 2-methyl-6-aminopurine (1445-08-5)

Guidance literature:

With formamide;

DOI:10.1021/ja01126a066

upstream raw materials:

4,6-diamino-5-nitroso-2-methylpyrimidine

N-(4,6-diamino-2-methyl-pyrimidin-5-yl)-thioformamide

6-chloro-2-methyl-7⁽⁹⁾H-purine

2,4-dichloro-2-methylpyrimidine

Downstream raw materials:

2,9-dimethyladenine

2,7-dimethyl-7H-purin-6-ylamine

2-methyladenosine

2-methyl-1,7-dihydro-purin-6-one

Refernces

• 1、 Secrist III, John A.. "Gene therapy of cancer: activation of nucleoside prodrugs with e. colipurine nucleoside phosphorylase". . p. 745 - 757. Retrieved 2007/10/03.