Morpholine, 4-(3-(4-(1,1-dimethylpropyl)phenyl)-2-methylpropyl)-2,6-dimethyl-

Base Information

• Chemical Name: Morpholine, 4-(3-(4-(1,1-dimethylpropyl)phenyl)-2-methylpropyl)-2,6-dimethyl-
• CAS No.: 67467-83-8
• Molecular Formula: C21H35NO
• Molecular Weight: 317.51
• DSSTox Substance ID: DTXSID80861010
• Nikkaji Number: J3.047.272A
• Mol file: 67467-83-8.mol

Synonyms:amorolfin hydrochloride;amorolfine;amorolfine hydrochloride;Locéryl;Loceryl;Locetar;Odenil;Ro 14-4767-002;Ro-14-4767-002

Chemical Property of Morpholine, 4-(3-(4-(1,1-dimethylpropyl)phenyl)-2-methylpropyl)-2,6-dimethyl-

Chemical Property:

• Appearance/Colour: white crystalline powder
• Boiling Point: 407.1 °C at 760 mmHg
• PKA: 7.33±0.10(Predicted)
• Flash Point: 119.6 °C
• PSA: 12.47000
• Density: 0.924 g/cm³
• LogP: 4.59990
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 5.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 317.271864740
• Heavy Atom Count: 23
• Complexity: 336

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2CC(OC(C2)C)C
• Uses: Amorolfine is available for topical use in 0.25% cream and 5% nail lacquer formulation for the treatment of onychomycosis in European countries and Japan. However, amorolfine is not approved in the USA for such indications. The major advantage of this new antimycotic drug presumably lies in its potential for use as 5% nail lacquer in the treatment of onychomycosis caused by dermatophytes and Candida spp. Antimycotic. Amorolfine is a novel antifungal agent used in the treatment of cutaneous fungal disease.