1-Bromo-5-chloropentane

Base Information

• Chemical Name: 1-Bromo-5-chloropentane
• CAS No.: 54512-75-3
• Molecular Formula: C5H10BrCl
• Molecular Weight: 185.491
• Hs Code.: 2903.40
• European Community (EC) Number: 259-193-7
• NSC Number: 50474
• UNII: LZF4NNM2WX
• DSSTox Substance ID: DTXSID3068960
• Nikkaji Number: J29.160I
• Wikidata: Q72453183
• Mol file: 54512-75-3.mol

Synonyms:Pentane, 1-bromo-5-chloro-;1-bromo-5-chloro-pentan;(1-Bromo-5-Chloropentane);

Chemical Property of 1-Bromo-5-chloropentane

Chemical Property:

• Appearance/Colour: clear colourless liquid
• Vapor Pressure: 0.271mmHg at 25°C
• Refractive Index: n20/D 1.484(lit.)
• Boiling Point: 211 °C at 760 mmHg
• Flash Point: 95 °C
• PSA: 0.00000
• Density: 1.367 g/cm³
• LogP: 2.79040
• Storage Temp.: Store below +30°C.
• Solubility.: Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)
• Water Solubility.: insoluble
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 4
• Exact Mass: 183.96544
• Heavy Atom Count: 7
• Complexity: 31.3

Purity/Quality:

99% ^*data from raw suppliers

1-Bromo-5-chloropentane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 23-24/25-37/39-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(CCCl)CCBr
• Uses: 1-Bromo-5-chloropentane, is used as an primary and secondary intermediate. It is also used as a intermediate in organic syntheses.

Technology Process of 1-Bromo-5-chloropentane

There total 12 articles about 1-Bromo-5-chloropentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-chloropentan-1-ol (5259-98-3) → 1-bromo-5-chloropentane (54512-75-3)

Guidance literature:

With phosphorus tribromide;

Reference yield:

→ 1-bromo-5-chloropentane (54512-75-3)

Guidance literature:

With phosphorus tribromide;

Reference yield:

5-chloropentyl 4-methylbenzenesulfonate (92948-25-9) + (S)-(+)-1-bromo-2-methylbutane (99032-67-4) → 1-bromo-5-chloropentane (54512-75-3) + C10H22 (1160105-89-4) + (R)-7-methylnonyl chloride (1224161-11-8)

Guidance literature:

(S)-(+)-1-bromo-2-methylbutane; With iodine; magnesium; In tetrahydrofuran; Inert atmosphere; Reflux;

5-chloropentyl 4-methylbenzenesulfonate; With dilithium tetrachlorocuprate; In tetrahydrofuran; at -60 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2010.02.028

upstream raw materials:

5-chloropentan-1-ol

N-(5-chloropentyl)benzamide

1-Chloropentane

1,1-Dichloroethylene

Downstream raw materials:

chloro-1 heptyne-6

[(5-chloropentyl)sulfanyl]benzene

1,5-diiodopentane

(R)-7-methylnonyl iodide

Refernces

• 1、 McCallum, Terry,Slavko, Ekaterina,Morin, Mathieu,Barriault, Louis. "Light-mediated deoxygenation of alcohols with a dimeric gold catalyst". supporting information. p. 81 - 85. Retrieved 2015/02/18.
• 2、 Maity, D. K.,Mohan, H.,Chattopadhyay, S.,Mittal, J. P.. "Formation, Stability, and Reactivity of Radical Cations of 1-Bromo-n-chloroalkanes in Aqueous Solution: A Pulse Radiolysis Study". . p. 12195 - 12203. Retrieved 2007/10/02.