Myristic anhydride

Base Information

• Chemical Name: Myristic anhydride
• CAS No.: 626-29-9
• Molecular Formula: C28H54 O3
• Molecular Weight: 438.735
• Hs Code.: 2915900090
• European Community (EC) Number: 210-941-0
• DSSTox Substance ID: DTXSID60870721
• Nikkaji Number: J94.929I
• Mol file: 626-29-9.mol

Synonyms:Myristic anhydride;626-29-9;tetradecanoyl tetradecanoate;Myristic acid anhydride;Tetradecanoic acid, anhydride;EINECS 210-941-0;Tetradecanoic acid, 1,1'-anhydride;MFCD00056151;Tetradecanoic anhydride;myristicanhydride;Tetradecanoic anhydride #;Myristic anhydride, 95%;SCHEMBL209749;RCRYHUPTBJZEQS-UHFFFAOYSA-;DTXSID60870721;C28H54O3;AKOS015950712;HY-W127537;BS-23653;CS-0185763;FT-0629056;M0484;D80696

Chemical Property of Myristic anhydride

Chemical Property:

• Vapor Pressure: 3.15E-08mmHg at 25°C
• Melting Point: 53-55 °C(lit.)
• Refractive Index: 1.4335 (estimate)
• Boiling Point: 448.3°C at 760 mmHg
• Flash Point: 203.8°C
• PSA: 43.37000
• Density: 0.892g/cm³
• LogP: 9.45840
• Storage Temp.: −20°C
• Solubility.: soluble in Toluene,Benzene
• XLogP3: 12.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 26
• Exact Mass: 438.40729558
• Heavy Atom Count: 31
• Complexity: 356

Purity/Quality:

98%,99%, ^*data from raw suppliers

Myristic Anhydride >95.0%(T) ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCCCC
• Uses: Myristic anhydride may be used in the following studies:As a reactant to synthesize cholesteryl myristate by reacting with cholesterol.As a reactant in the synthesis of 1,2-dimyristoyl-sn-glycero-3-phosphocholine by acylating sn-glycero-3-phosphocholine.As a reagent in the synthesis of 3-(bis-{2-(tert-butyldimethylsilyloxy)ethyl}amino)propane-1,2-diol, an intermediate of cationic lipid.As a reactant to synthesize neryl myristate by reacting with nerol.As a reagent to synthesize myristoylated t-butylglutamic acid by myristoylation of γ-tert-butoxy-glutamic acid.

Technology Process of Myristic anhydride

There total 6 articles about Myristic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

n-tetradecanoic acid (544-63-8) → myristic anhydride (626-29-9)

Guidance literature:

With acetic anhydride; at 140 ℃; for 0.5h;

DOI:10.1007/s11746-012-2165-0

Reference yield: 92.0%

tetradecanoyl chloride (112-64-1) → myristic anhydride (626-29-9)

Guidance literature:

With sodium hydroxide; tetrabutyl-ammonium chloride; In toluene; at -10 ℃; for 3h;

DOI:10.1016/S0040-4020(01)81698-7

Reference yield:

tetradecanoyl chloride (112-64-1) → myristic anhydride (626-29-9)

Guidance literature:

at 100 ℃;

upstream raw materials:

acetic anhydride

n-tetradecanoic acid

tetradecanoyl chloride

Downstream raw materials:

myristylaldehyde

glycerol 1,3-dimyristate

N-tetradecanoyl-L-glutamic acid

C₅₈H₇₂F₂N₆O₁₂S

Refernces

• 1、 Wang, Jinkang,Guo, Xin,Xu, Yuhong,Barron, Lee,Szoka Jr., Francis C.. "Synthesis and characterization of long chain alkyl acyl carnitine esters. Potentially biodegradable cationic lipids for use in gene delivery". . p. 2207 - 2215. Retrieved 2007/10/03.
• 2、 Roulleau, Fabienne,Plusquellec, Daniel,Brown, Eric. "UNE METHODE SIMPLE ET RAPIDE DE PREPARATION DES ANHYDRIDES D'ACIDES CARBOXYLIQUES A PARTIR DE LEURS CHLORURES D'ACIDES, AVEC CATALYSE PAR TRANSFERT DE PHASE". . p. 4195 - 4196. Retrieved 2007/10/02.