Stachyose hydrate

Base Information

• Chemical Name: Stachyose hydrate
• CAS No.: 470-55-3
• Molecular Formula: C24H42O21
• Molecular Weight: 666.585
• Hs Code.: 2932999099
• DSSTox Substance ID: DTXSID00861971
• Wikidata: Q105277573
• Mol file: 470-55-3.mol

Synonyms:stachyose;stachyose hydrate;stachyose tetrahydrate

Chemical Property of Stachyose hydrate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 170°C
• Refractive Index: 1.689
• Boiling Point: 1044.2oC at 760mmHg
• PKA: 12.81±0.70(Predicted)
• Flash Point: 585.3oC
• PSA: 347.83000
• Density: 1.84g/cm3
• LogP: -9.74720
• Solubility.: H2O: 50 mg/mL, clear, colorless
• XLogP3: -8
• Hydrogen Bond Donor Count: 14
• Hydrogen Bond Acceptor Count: 21
• Rotatable Bond Count: 11
• Exact Mass: 666.22185834
• Heavy Atom Count: 45
• Complexity: 933

Purity/Quality:

99%, ^*data from raw suppliers

Stachyose ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OCC3C(C(C(C(O3)OC4(C(C(C(O4)CO)O)O)CO)O)O)O)O)O)O)O)O)O)O
• Uses: Stachyose is widely present in legumes and are indigestible by humans because of a lack of α-galactosidase. As a result, these compounds undergo fermentation in the colon with the concomitant production of CO2, H2, and CH4, commonly referred to as flatulence. Stachyose - 70% is used in method for preparing high-purity Stachyose from Rehmannia glutinosa by combining subcritical and microbial fermentation.

Technology Process of Stachyose hydrate

There total 5 articles about Stachyose hydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

D-raffinose (512-69-6) → D-Galactose (59-23-4) + stachyose (470-55-3)

Guidance literature:

With recombinant Aspergillus nidulans FGSC GH36 α-galactosidase; at 37 ℃; for 1h; pH=5; Concentration; regioselective reaction; Kinetics; aq. acetate buffer; Enzymatic reaction;

DOI:10.1111/j.1742-4658.2010.07763.x

Reference yield: 12.0%

D-melibiose (536-11-8,645-03-4,902-54-5,3031-35-4,4604-26-6,5340-95-4,5995-99-3,5996-00-9,13299-20-2,13299-21-3,15548-40-0,16750-26-8,16967-97-8,23339-29-9,24822-33-1,33428-65-8,34674-94-7,35867-21-1,37169-69-0,37169-72-5,38533-27-6,50271-70-0,65207-30-9,82729-73-5,95463-59-5,100427-99-4,100430-37-3,100483-14-5,102572-70-3,110658-40-7,123809-47-2,140461-60-5,143615-15-0) + Sucrose (57-50-1) → O-α-D-galactopyranosyl-(1->6)-)-O-α-D-galactopyranosyl-(1->6)-O-D-glucopyranose (499-39-8) + stachyose (470-55-3) + D-raffinose (512-69-6)

Guidance literature:

at 40 ℃; for 15h; Product distribution; α-galactosidase from Candida guilliermondii H-404, acetate buffer (pH 4.5); transgalactosylation of various saccharides and alcohols catalyzed by α-galactosidase from Candida guilliermondii, transfer ratio, acceptor specificities;

DOI:10.1271/bbb.59.619

Reference yield:

D-raffinose (512-69-6) → O-α-D-galactopyranosyl-(1->3)-O-α-D-glucopyranosyl-(1->2)-β-D-fructofuranoside (2650-46-6) + O-α-D-galactopyranosyl-(1->3)-O-α-D-galactopyranosyl-(1->6)-O-α-D-glucopyranosyl-(1->2)-β-D-fructofuranoside + O-α-D-galactopyranosyl-(1->3)-O-α-D-galactopyranosyl-(1->6)-O-α-D-galactopyranosyl(1->6)-O-α-D-glucopyranosyl-(1->2)-β-D-fructofuranoside + ajugose + stachyose (470-55-3) + α-D-galactopyranosyl-(1→6)-α-D-galactopyranosyl-(1→6)-α-D-galactopyranosyl-(1→6)-α-D-glucopyranosyl-(1→2)-β-D-fructofuranoside (546-62-3)

Guidance literature:

With disodium hydrogenphosphate; Citric acid buffer; Product distribution; Pycnoporus cinnabarinus α-galactosidase, 60 deg C, 6 h, then boiling for 5 min;

upstream raw materials:

D-raffinose

D-melibiose

Sucrose

4-nitrophenyl α-D-galactoside

Downstream raw materials:

D-Fructose

O-α-D-galactopyranosyl-(1->6)-)-O-α-D-galactopyranosyl-(1->6)-O-D-glucopyranose

D-Galactose

D-melibiose

Refernces

• 1、 Zhao, Yue-Tao,Niu, Shan,Huang, Lu-Bai,Wang, Ji-Ming,Yin, Zhao-Jun,Li, Qing,Li, Zhong-Jun. "Synthesis of raffinose family oligosaccharides by regioselective de-O-benzylation with Co2(CO)8/Et3SiH/CO system". . p. 5022 - 5028. Retrieved 2013/06/27.
• 2、 Mitsutomi, Masaru,Ohtakara, Akira. "Isolation and Identification of Oligosaccharides Produced from Raffinose by Transgalactosylation Reaction of Thermostable α-Galactosidase from Pycnoporus cinnabarinus". . p. 2305 - 2312. Retrieved 2007/10/02.