Stronghold

Base Information

• Chemical Name: Stronghold
• CAS No.: 165108-07-6
• Molecular Formula: C₄₃H₆₃NO₁₁
• Molecular Weight: 769.973
• European Community (EC) Number: 811-481-9,815-979-7
• DSSTox Substance ID: DTXSID801339341
• Wikipedia: Selamectin
• Wikidata: Q2267471
• NCI Thesaurus Code: C75233
• Mol file: 165108-07-6.mol

Synonyms:25-cyclohexyl-25-de(1-methylpropyl)-5-deoxy-22 23-dihydro-5-(hydroxyimino)-avermectin B1 monosaccharide;selamectin

Chemical Property of Stronghold

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.618
• Boiling Point: 917 °C at 760 mmHg
• PKA: 10.18±0.70(Predicted)
• Flash Point: 508.4 °C
• PSA: 154.73000
• Density: 1.35 g/cm³
• LogP: 6.06980
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 4
• Exact Mass: 769.44011183
• Heavy Atom Count: 55
• Complexity: 1550

Purity/Quality:

99%, ^*data from raw suppliers

SelamectinimpurityB 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCC2(CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5=NO)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)O)OC)C)OC1C7CCCCC7
• Isomeric SMILES: C[C@H]1CC[C@]2(C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]\5[C@@]4([C@@H](C=C(/C5=N\O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)\C)O[C@@H]1C7CCCCC7
• Uses: Antiparasitic (veterinary). Selamectin is used in the preparation of new antiparasitic agents and insecticides.

Technology Process of Stronghold

There total 8 articles about Stronghold which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C43H62O11 → [3H]-Selamectin (165108-07-6,220119-17-5)

Guidance literature:

With hydroxylamine hydrochloride; In water; isopropyl alcohol; at 40 ℃; for 7h;

Reference yield:

C50H72O14 → [3H]-Selamectin (165108-07-6,220119-17-5)

Guidance literature:

With hydroxylamine hydrochloride; In 1,4-dioxane; methanol; water; at 40 ℃; for 4h; Solvent; Temperature; Industrial scale;

Reference yield:

C43H62O11 → C43H63NO11 (165108-07-6,220119-17-5)

Guidance literature:

With hydroxylamine hydrochloride; In water; isopropyl alcohol; at 10 - 30 ℃; Temperature; Inert atmosphere; Large scale;

upstream raw materials:

doramectin

doramectin

C₅₀H₇₆O₁₄

Refernces

• 1、 -. "Preparation method of high-purity celecampin". . . Retrieved 2019/07/25.
• 2、 -. "NEW SYNTHESIS PROCESS OF ANTIPARASITIC DRUG SELAMECTIN". . . Retrieved 2015/02/25.