4-AMINO-6-METHYL-1,3,5-TRIAZIN-2-OL

Base Information

• Chemical Name: 4-AMINO-6-METHYL-1,3,5-TRIAZIN-2-OL
• CAS No.: 16352-06-0
• Molecular Formula: C4H6N4O
• Molecular Weight: 126.118
• Hs Code.: 2933699090
• Mol file: 16352-06-0.mol

Synonyms:1,3,5-Triazin-2(1H)-one,4-amino-6-methyl- (9CI);s-Triazin-2-ol, 4-amino-6-methyl- (6CI,7CI,8CI);4-Amino-6-methyl-1,3,5-triazin-2-ol;Acetoguanide;IN-B 5528;

Chemical Property of 4-AMINO-6-METHYL-1,3,5-TRIAZIN-2-OL

Chemical Property:

• Vapor Pressure: 0.0564mmHg at 25°C
• Melting Point: >350 °C
• Refractive Index: 1.731
• Boiling Point: 233.3 °C at 760 mmHg
• PKA: 7.42±0.70(Predicted)
• Flash Point: 94.9 °C
• PSA: 84.92000
• Density: 1.67 g/cm³
• LogP: 0.04900
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility.: Aqueous Acid (Slightly), Methanol (Slightly, Heated, Sonicated)

Purity/Quality:

98%min ^*data from raw suppliers

Acetoguanide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Acetoguanide is a degradation product of the sulfonylurea herbicide Iodosulfuron.

Technology Process of 4-AMINO-6-METHYL-1,3,5-TRIAZIN-2-OL

There total 18 articles about 4-AMINO-6-METHYL-1,3,5-TRIAZIN-2-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-methoxy-6-methyl-1,3,5-triazin-2-amine (1668-54-8) → 4-amino-6-methyl-1,3,5-triazine-2-ol (16352-06-0)

Guidance literature:

With sodium hydroxide; In dimethyl sulfoxide; Ambient temperature;

DOI:10.1021/jf970299d

Reference yield: 21.0%

C30H26N4O8 (189129-08-6) → 6-methyl-5-azacytosine (16352-06-0) + 2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl 2,3,5-tri-O-benzoyl-β-D-ribofuranoside (62374-52-1) + 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose (67525-66-0) + C30H26N4O8 (189129-04-2) + 2',3',5'-tri-O-benzoyl-6-methyl-5-azacytidine (105330-91-4) + 1,3,5-tri-O-benzoyl-α-D-ribofuranoside (22224-41-5)

Guidance literature:

With tin(IV) chloride; In 1,2-dichloro-ethane; for 3h; Product distribution; Ambient temperature; other reagent, reaction time;

DOI:10.1080/07328319708002528

Reference yield: 6.0%

2',3',5'-tri-O-benzoyl-6-methyl-5-azacytidine (105330-91-4) → 6-methyl-5-azacytosine (16352-06-0) + 2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl 2,3,5-tri-O-benzoyl-β-D-ribofuranoside (62374-52-1) + 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose (67525-66-0) + C30H26N4O8 (189129-04-2) + 1,3,5-tri-O-benzoyl-α-D-ribofuranoside (22224-41-5)

Guidance literature:

With tin(IV) chloride; In 1,2-dichloro-ethane; for 3h; Product distribution; Ambient temperature;

DOI:10.1080/07328319708002528

upstream raw materials:

N¹-acetyl-N³-cyanoguanidine

acetylcarbamoyl-guanidine

2,4-bis(trichloromethyl)-6-methyl-1,3,5-triazine

acetic anhydride

Downstream raw materials:

4-Methyl-6-(4-methyl-3-phenyl-quinolin-2-ylmethoxy)-[1,3,5]triazin-2-ylamine

4-amino-6-methyl-1-[(8-methyl-2-phenylquinolin-3-yl)methyl]-1,3,5-triazin-2(1H)-one

4-[(8-methyl-2-phenylquinolin-3-yl)methoxy]-6-methyl-1,3,5-triazin-2-amine

6-methyl-1,3,5-triazine-2,4(1H,3H)-dione

Refernces

• 1、 Vulliet,Emmelin,Grenier-Loustallot,Paisse,Chovelon. "Simulated sunlight-induced photodegradations of triasulfuron and cinosulfuron in aqueous solutions". . p. 1081 - 1088. Retrieved 2002.
• 2、 Hanna, Naeem B.,Zajicek, Jaroslav,Piskala, Alois. "6-Methyl-5-azacytidine - Synthesis, conformational properties and biological activity. A comparison of molecular conformation with 5- azacytidine". . p. 129 - 144. Retrieved 2007/10/03.