BENZO(F)ISOQUINOLINE

Base Information

• Chemical Name: BENZO(F)ISOQUINOLINE
• CAS No.: 229-67-4
• Molecular Formula: C₁₃H₉N
• Molecular Weight: 179.221
• Hs Code.: 2933990090
• Mol file: 229-67-4.mol

Synonyms:2-Azaphenanthrene

Chemical Property of BENZO(F)ISOQUINOLINE

Chemical Property:

• Vapor Pressure: 3.18E-05mmHg at 25°C
• Boiling Point: 366°Cat760mmHg
• Flash Point: 166.3°C
• PSA: 12.89000
• Density: 1.187g/cm³
• LogP: 3.38800

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BENZO(F)ISOQUINOLINE

There total 13 articles about BENZO(F)ISOQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4-[2-(2-iodovinyl)phenyl]pyridine (1375801-19-6) → benzo[f]isoquinoline (229-67-4)

Guidance literature:

In acetonitrile; at 20 ℃; for 16h; UV-irradiation; Inert atmosphere; Pyrex filter;

DOI:10.1016/j.tet.2012.03.056

Reference yield: 63.0%

Benzo[f]isoquinoline 3-oxide (89705-58-8) → benzo[f]isoquinoline (229-67-4)

Guidance literature:

With tetraphenylporphinatoiron(II)(pyridine)2; In dichloromethane; for 45h; Ambient temperature;

Reference yield: 60.0%

2-(3-methyl-pyridin-4-yl)-benzaldehyde (1086561-23-0) → benzo[f]isoquinoline (229-67-4)

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.tet.2008.09.015

upstream raw materials:

Benzo[f]isoquinoline 3-oxide

1-(2-formamidoylethyl)naphthalene

4-(2-ethynylphenyl)pyridine

2-naphthalen-1-yl-ethylamine

Refernces

• 1、 Galiazzo et al.. "-". . p. 3717,3718,3719. Retrieved 1966.
• 2、 Fu, Wai Chung,Wang, Zheng,Chan, Wesley Ting Kwok,Lin, Zhenyang,Kwong, Fuk Yee. "Regioselective Synthesis of Polycyclic and Heptagon-embedded Aromatic Compounds through a Versatile π-Extension of Aryl Halides". supporting information. p. 7166 - 7170. Retrieved 2017/06/13.
• 3、 Mamane, Victor,Lou?rat, Frédéric,Iehl, Julien,Abboud, Mohamed,Fort, Yves. "A general and efficient method for the synthesis of benzo-(iso)quinoline derivatives". . p. 10699 - 10705. Retrieved 2008/12/23.