Butyl chloroformate

Base Information Edit

Chemical Name:Butyl chloroformate
CAS No.:592-34-7
Molecular Formula:C5H9 Cl O2
Molecular Weight:136.578
Hs Code.:2915.13
European Community (EC) Number:209-750-5
ICSC Number:1593
NSC Number:8428
UN Number:2743
UNII:3TGX130CB0
DSSTox Substance ID:DTXSID7060461
Nikkaji Number:J95.611B
Wikidata:Q22668707
Mol file:592-34-7.mol

Synonyms:Formicacid, chloro-, butyl ester (6CI,7CI,8CI); Butan-1-yl chloroformate;Butoxycarbonyl chloride; Butyl chlorocarbonate; Butyl chloroformate;Chloroformic acid butyl ester; NSC 8428; n-Butyl chloroformate

Suppliers and Price of Butyl chloroformate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Butyl chloroformate
5g
$ 65.00

Sigma-Aldrich
Butyl chloroformate 98%
100g
$ 76.00

Biosynth Carbosynth
Butyl chloroformate
2 Kg
$ 500.00

Biosynth Carbosynth
Butyl chloroformate
1 Kg
$ 300.00

Biosynth Carbosynth
Butyl chloroformate
500 g
$ 200.00

Biosynth Carbosynth
Butyl chloroformate
250 g
$ 125.00

Biosynth Carbosynth
Butyl chloroformate
5 Kg
$ 900.00

American Custom Chemicals Corporation
N-BUTYL CHLOROFORMATE 95.00%
1G
$ 628.68

Alfa Aesar
n-Butyl chloroformate, 98%
250g
$ 59.10

Alfa Aesar
n-Butyl chloroformate, 98%
100g
$ 28.50

Total 47 raw suppliers

Chemical Property of Butyl chloroformate Edit

Chemical Property:

Appearance/Colour:clear liquid
Vapor Pressure:2.42 psi ( 20 °C)
Melting Point:-70 ºC
Refractive Index:n20/D 1.412(lit.)
Boiling Point:142 C
Flash Point:39 ºC
PSA：26.30000
Density:1.074
LogP:2.16190
Storage Temp.:2-8°C
Sensitive.:Moisture Sensitive
Water Solubility.:DECOMPOSES
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:136.0291072
Heavy Atom Count:8
Complexity:72.8
Transport DOT Label:Poison Inhalation Hazard Corrosive Flammable Liquid

Purity/Quality:

99% ^*data from raw suppliers

Butyl chloroformate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 10-23-34
Safety Statements: 26-36-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Toxic Gases & Vapors -> Acid Halides
Canonical SMILES:CCCCOC(=O)Cl
Inhalation Risk:A harmful contamination of the air will be reached very quickly on evaporation of this substance at 20 °C.
Effects of Short Term Exposure:The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the vapour may cause lung oedema. The effects may be delayed.
Uses Butyl Chloroformate is a reactant in the preparation of Lapatinib derivatives as HER1/HER2 targeting antitumor drugs.

Technology Process of Butyl chloroformate

There total 13 articles about Butyl chloroformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: methyl 4-(6-amino-2,3,5-trimethylindol-1-ylmethyl)-3-methoxybenzoate

: methyl 4-[6-(butoxycarbonyl)amino-2,3,5-trimethylindol-1-ylmethyl]-3-methoxybenzoate

: 592-34-7
carbonochloridic acid, butyl ester

Guidance literature:

Reference yield: 96.0%

: 32315-10-9
bis(trichloromethyl) carbonate

: 71-36-3
butan-1-ol

: 592-34-7
carbonochloridic acid, butyl ester

Guidance literature:: bis(trichloromethyl) carbonate; With sodium carbonate; N,N-dimethyl-formamide; In toluene; at 0 ℃; for 0.5h;

butan-1-ol; In toluene; at 0 ℃; for 8.5h;