Chaetoglobosins

Base Information

• Chemical Name: Chaetoglobosins
• CAS No.: 50335-03-0
• Molecular Formula: C32H36 N2 O5
• Molecular Weight: 528.648
• Hs Code.: 2941900000
• European Community (EC) Number: 813-006-0
• Wikipedia: Chaetoglobosin_A
• Mol file: 50335-03-0.mol

Synonyms:chaetoglobosin A;chaetoglobosin B;chaetoglobosin C;chaetoglobosin D;chaetoglobosin E;chaetoglobosin F;chaetoglobosin K;chaetoglobosin Q;chaetoglobosin R;chaetoglobosin T;chaetoglobosin U;chaetoglobosin V;chaetoglobosin W;chaetoglobosin Y;chaetoglobosins;penochalasin K

Chemical Property of Chaetoglobosins

Chemical Property:

• Vapor Pressure: 2.78E-26mmHg at 25°C
• Melting Point: 188°C
• Refractive Index: 1.5800 (estimate)
• Boiling Point: 789.7 °C at 760 mmHg
• PKA: 17.32±0.30(Predicted)
• Flash Point: 431.4 °C
• PSA: 111.79000
• Density: 1.3 g/cm³
• LogP: 4.16120
• Storage Temp.: ?20°C
• Solubility.: DMSO: soluble10mg/mL
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 528.26242225
• Heavy Atom Count: 39
• Complexity: 1140

Purity/Quality:

98%Min ^*data from raw suppliers

Chaetoglobosin A ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CC=CC2C3C(O3)(C(C4C2(C(=O)C=CC(=O)C(C(=C1)C)O)C(=O)NC4CC5=CNC6=CC=CC=C65)C)C
• Isomeric SMILES: C[C@H]1CC=C[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@@]2(C(=O)C=CC(=O)[C@@H](C(=C1)C)O)C(=O)N[C@H]4CC5=CNC6=CC=CC=C65)C)C
• Description: Chaetoglobosin A (50335-03-0) is a cytochalasin analog which targets filamentous actin. Displays cytotoxic effects against human colorectal HCT116 cells, IC50=3.15 μM.1 Preferentially induces apoptosis in chronic lymphocytic leukemia cells via targeting the cytoskeleton.2 Enhances the fibrinolytic activity of vascular endothelial cells.3
• Uses: Chaetoglobosin A is a mycotoxic cytochalasan compound.