Dimethyl-p-tolylphosphine

Base Information

• Chemical Name: Dimethyl-p-tolylphosphine
• CAS No.: 20676-64-6
• Molecular Formula: C9H13P
• Molecular Weight: 152.176
• European Community (EC) Number: 243-959-2
• DSSTox Substance ID: DTXSID60942876
• Nikkaji Number: J280.642H
• Wikidata: Q82919872
• Mol file: 20676-64-6.mol

Synonyms:Dimethyl-p-tolylphosphine;20676-64-6;dimethyl-(4-methylphenyl)phosphane;EINECS 243-959-2;dimethyl(4-methylphenyl)phosphine;Phosphine,dimethyl(4-methylphenyl)-;dimethyl-p-tolyl phosphane;C9H13P;SCHEMBL7558573;DTXSID60942876;C9-H13-P;DIMETHYL(4-METHYLPHENYL)PHOSPHANE

Chemical Property of Dimethyl-p-tolylphosphine

Chemical Property:

• Vapor Pressure: 0.248mmHg at 25°C
• Boiling Point: 212.7 °C at 760 mmHg
• Flash Point: 83.7 °C
• PSA: 13.59000
• LogP: 2.36180
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 152.075487412
• Heavy Atom Count: 10
• Complexity: 90.9

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)P(C)C

Technology Process of Dimethyl-p-tolylphosphine

There total 6 articles about Dimethyl-p-tolylphosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-tolyldichlorophosphine (1005-32-9) + methyllithium (917-54-4) → dimethyl(4-tolyl)phosphine (20676-64-6)

Guidance literature:

In diethyl ether; at -78 - 20 ℃; for 2.4h; Inert atmosphere;

DOI:10.1002/ejic.201301203

Reference yield:

4-methoxymethylphenylmagnesium bromide (96259-22-2) → dimethyl(4-tolyl)phosphine (20676-64-6)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran

2: lithium aluminium hydride / dioxane / 60 h / Heating

With lithium aluminium tetrahydride; In tetrahydrofuran; 1,4-dioxane;

Reference yield:

1-(Dimethyl-phosphinothioyl)-4-methoxymethyl-benzene (86605-74-5) → dimethyl(4-tolyl)phosphine (20676-64-6) + (4-Methoxymethyl-phenyl)-dimethyl-phosphane (86605-84-7)

Guidance literature:

With lithium aluminium tetrahydride; In 1,4-dioxane; for 60h; Heating;

upstream raw materials:

methyl magnesium iodide

p-tolyldichlorophosphine

dimethyl zinc(II)

1-(Dimethyl-phosphinothioyl)-4-methoxymethyl-benzene

Downstream raw materials:

4-(Dimethylphosphinoyl)-benzoic Acid

bis(η-cyclopentadienyl)hydrido(4-tolylphosphido)tungsten

1-(methyl-p-tolylphosphinoyl)-3-methylbutan-2-ol

1-(methyl-p-tolylphosphinoyl)-2-methylpropan-2-ol

Refernces

• 1、 Solomon, Sophia A.,Allen, Lucy K.,Dane, Sarah B. J.,Wright, Dominic S.. "Base-Induced 1,3-Sigmatropic rearrangement of mesitylphosphonium salts". supporting information. p. 1615 - 1619. Retrieved 2014/04/17.
• 2、 Kawakami, Yuhsuke,Murthy, R. Aswathanarayana,Yamashita, Yuya. "HYDROXY FUNCTIONALIZED TERTIARY PHOSPHINES". . p. 427 - 434. Retrieved 2007/10/02.