Eriocalyxin B

Base Information

• Chemical Name: Eriocalyxin B
• CAS No.: 84745-95-9
• Molecular Formula: C₂₀H₂₄O₅
• Molecular Weight: 344.408
• Mol file: 84745-95-9.mol

Synonyms:Kaura-2,16-diene-1,15-dione,7,20-epoxy-6,7- dihydroxy-,(6a,7R)-;Rabdosianone I;

Chemical Property of Eriocalyxin B

Chemical Property:

• Boiling Point: 551.1 °C at 760 mmHg
• PKA: 11.05±0.60(Predicted)
• Flash Point: 198.9 °C
• PSA: 83.83000
• Density: 1.37 g/cm³
• LogP: 1.38900

Purity/Quality:

99%, ^*data from raw suppliers

EriocalyxinB 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Eriocalyxin B

There total 6 articles about Eriocalyxin B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C23H34O5Si → (±)-eriocalyxin B (84745-95-9)

Guidance literature:

With palladium diacetate; In acetonitrile; at 20 ℃; for 6h;

DOI:10.1038/s41467-018-03546-9

Reference yield:

C20H28O4 → (±)-eriocalyxin B (84745-95-9)

Guidance literature:

Multi-step reaction with 6 steps

1: selenium(IV) oxide; tert.-butylhydroperoxide / dichloromethane / 24 h

2: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h

3: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / tetrahydrofuran; dimethyl sulfoxide / 0 - 20 °C

4: Jones reagent / water; acetone / 0.25 h / 0 °C

5: sodium iodide / acetonitrile / 12 h / 0 - 20 °C

6: palladium diacetate / acetonitrile / 6 h / 20 °C

With tert.-butylhydroperoxide; selenium(IV) oxide; lithium aluminium tetrahydride; Jones reagent; palladium diacetate; sodium iodide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; acetone; acetonitrile; 4: |Jones Oxidation / 6: |Saegusa Oxidation;

DOI:10.1038/s41467-018-03546-9

Reference yield:

C20H28O5 → (±)-eriocalyxin B (84745-95-9)

Guidance literature:

Multi-step reaction with 5 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h

2: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / tetrahydrofuran; dimethyl sulfoxide / 0 - 20 °C

3: Jones reagent / water; acetone / 0.25 h / 0 °C

4: sodium iodide / acetonitrile / 12 h / 0 - 20 °C

5: palladium diacetate / acetonitrile / 6 h / 20 °C

With lithium aluminium tetrahydride; Jones reagent; palladium diacetate; sodium iodide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; water; dimethyl sulfoxide; acetone; acetonitrile; 3: |Jones Oxidation / 5: |Saegusa Oxidation;

DOI:10.1038/s41467-018-03546-9

Refernces