1,3-Dichlorotetramethyldisiloxane

Base Information

• Chemical Name: 1,3-Dichlorotetramethyldisiloxane
• CAS No.: 2401-73-2
• Deprecated CAS: 1357297-22-3
• Molecular Formula: C4H12Cl2OSi2
• Molecular Weight: 203.216
• Hs Code.: 29319090
• European Community (EC) Number: 219-278-1
• DSSTox Substance ID: DTXSID6062381
• Nikkaji Number: J216.043I
• Wikidata: Q72468285
• Mol file: 2401-73-2.mol

Synonyms:1,3-Dichlorotetramethyldisiloxane;2401-73-2;1,3-Dichloro-1,1,3,3-tetramethyldisiloxane;chloro-[chloro(dimethyl)silyl]oxy-dimethylsilane;Disiloxane, 1,3-dichloro-1,1,3,3-tetramethyl-;EINECS 219-278-1;MFCD00018088;1,1,3,3-tetramethyl-1,3-dichlorodisiloxane;C4H12Cl2OSi2;Oxybis(chlorodimethylsilane);bis(chlorodimethylsilyl)ether;SCHEMBL297046;C4-H12-Cl2-O-Si2;Sym-dichlorotetramethyldisiloxane;DTXSID6062381;DMEXFOUCEOWRGD-UHFFFAOYSA-;1,3-dichlorotetramethyl disiloxane;AKOS008901313;FS-5411;D2334;FT-0606655;chloro[(chlorodimethylsilyl)oxy]dimethylsilane;1,3-dichloro-1,1,3,3,-tetramethyldisiloxane;1,3-Dichloro-1,1,3,3-tetramethyl disiloxane;chloro-(chloro-dimethylsilyl)oxy-dimethylsilane;D90047;S06225;A878056;1,3-Dichloro-1,1,3,3-tetramethyldisiloxane, 97%;J-015314

Chemical Property of 1,3-Dichlorotetramethyldisiloxane

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 8.53mmHg at 25°C
• Melting Point: -37 °C
• Refractive Index: n20/D 1.407(lit.)
• Boiling Point: 138 °C at 760 mmHg
• Flash Point: 33 °C
• PSA: 9.23000
• Density: 1.041 g/cm³
• LogP: 2.88420
• Storage Temp.: Flammables area
• Sensitive.: Moisture Sensitive
• Water Solubility.: Reacts with water.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 201.9803735
• Heavy Atom Count: 9
• Complexity: 92.7

Purity/Quality:

99.5% ^*data from raw suppliers

1,3-Dichloro-1,1,3,3-tetramethyldisiloxane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,C
• Hazard Codes: F,C
• Statements: 11-34
• Safety Statements: 16-26-27-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[Si](C)(O[Si](C)(C)Cl)Cl
• Uses: 1,3-Dichlorotetramethyldisiloxane is used to produce 1,1,3,3-tetramethyl-disiloxane-1,3-diol. It is also used as Chemical Additives. Pharmaceutical intermediates.

Technology Process of 1,3-Dichlorotetramethyldisiloxane

There total 24 articles about 1,3-Dichlorotetramethyldisiloxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.6%

1,1,3,3-Tetramethyldisiloxane (3277-26-7) → 1,1,3,3-tetramethyl-1,3-dichlorodisiloxane (2401-73-2)

Guidance literature:

With trichloroisocyanuric acid; In dichloromethane; Heating;

DOI:10.1016/j.jorganchem.2006.12.032

Reference yield: 78.0%

dimethyl sulfoxide (67-68-5,8070-53-9) + dimethylsilicon dichloride (75-78-5,30107-43-8) → chloro-methylsulfanyl-methane (2373-51-5) + 1,1,3,3-tetramethyl-1,3-dichlorodisiloxane (2401-73-2) + 1,5-dichlorohexamethyltrisiloxane (3582-71-6)

Guidance literature:

at 0 - 20 ℃; for 3h;

DOI:10.1134/S001250081308003X

Reference yield: 78.0%

dimethylsilicon dichloride (75-78-5,30107-43-8) → 1,1,3,3-tetramethyl-1,3-dichlorodisiloxane (2401-73-2) + 1,5-dichlorohexamethyltrisiloxane (3582-71-6)

Guidance literature:

With dimethyl sulfoxide; at 0 - 20 ℃; for 3h; Reagent/catalyst; Solvent;

DOI:10.1134/S001250081308003X

upstream raw materials:

Dimethyl ether

dimethylsilicon dichloride

1,1,3,3-Tetramethyldisiloxane

Hexamethyldisiloxane

Downstream raw materials:

tetramethyldisiloxane-1,3-diyl diacetate

Hexamethyl(silacyclohexyl)cyclotetrasiloxan

2,2,5,5-tetramethyl-3-phenyl-1,2,5-oxadisilolane

2,2,5,5-tetramethyl-3,3-diphenyl-[1,2,5]oxadisilolane

Refernces

• 1、 Hafner, Thomas,Torvisco, Ana,Uhlig, Frank. "Building blocks for oligomeric siloxanes –selective chlorination of hydrido-siloxanes". supporting information. p. 1 - 4. Retrieved 2018/09/11.
• 2、 Basenko,Soldatenko,Voronkov. "Efficient method for the synthesis of symmetrical α,ω-dichloro- 1,1,3,3-tetraorganyldisiloxanes". . p. 203 - 206. Retrieved 2013/09/23.