(s)-1,2-Diphenylethanol

Base Information

• Chemical Name: (s)-1,2-Diphenylethanol
• CAS No.: 5773-56-8
• Molecular Formula: C₁₄H₁₄O
• Molecular Weight: 198.265
• Hs Code.: 29062900
• UNII: OV6YI1OG6G
• DSSTox Substance ID: DTXSID20362455
• Nikkaji Number: J900.333I
• Wikidata: Q82145548
• Mol file: 5773-56-8.mol

Synonyms:(s)-1,2-diphenylethanol;5773-56-8;(1S)-1,2-diphenylethanol;OV6YI1OG6G;(+)-1,2-Diphenylethanol;(S)-(+)-1,2-DIPHENYLETHANOL;1,2-Diphenylethanol, (+)-;(1S)-1,2-Diphenylethan-1-ol;UNII-OV6YI1OG6G;(S)-alpha-Benzylphenylmethanol;(R,S)-1,2-Diphenyl-ethanol;SCHEMBL4355212;DTXSID20362455;MFCD06658925;(S)-.ALPHA.-BENZYLPHENYLMETHANOL

Chemical Property of (s)-1,2-Diphenylethanol

Chemical Property:

• Vapor Pressure: 0.000301mmHg at 25°C
• Melting Point: 67.5°C
• Refractive Index: 1.5680 (estimate)
• Boiling Point: 308.1°Cat760mmHg
• Flash Point: 129.4°C
• PSA: 20.23000
• Density: 1.094g/cm³
• LogP: 2.96270
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 198.104465066
• Heavy Atom Count: 15
• Complexity: 166

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC(C2=CC=CC=C2)O
• Isomeric SMILES: C1=CC=C(C=C1)C[C@@H](C2=CC=CC=C2)O

Technology Process of (s)-1,2-Diphenylethanol

There total 270 articles about (s)-1,2-Diphenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

benzoyl chloride (98-88-4) → 1,2-Diphenylethanol (5773-56-8,614-29-9) + 1,2-diphenyl-1,2-ethanediol (492-70-6,655-48-1,2325-10-2,38270-73-4,52340-78-0,579-43-1) + 2-hydroxy-2-phenylacetophenone (119-53-9,579-44-2) + benzyl alcohol (100-51-6,185532-71-2)

Guidance literature:

With samarium diiodide; phosphoric acid; In tetrahydrofuran; for 0.000833333h; Ambient temperature;

DOI:10.1016/S0040-4020(01)80441-5

Reference yield: 36.0%

2-hydroxy-2-phenylacetophenone (119-53-9,579-44-2) → 1,2-Diphenylethanol (5773-56-8,614-29-9) + 1,2-diphenyl-1,2-ethanediol (492-70-6,655-48-1,2325-10-2,38270-73-4,52340-78-0,579-43-1)

Guidance literature:

With samarium diiodide; lithium amide; In tetrahydrofuran; methanol; for 0.000833333h; Ambient temperature;

DOI:10.1016/0040-4039(91)80819-R

Reference yield: 22.0%

cis-stilben (645-49-8) → 1,2-Diphenylethanol (5773-56-8,614-29-9) + benzyl alcohol (100-51-6,185532-71-2)

Guidance literature:

With sodium tetrahydroborate; tetramethyl ammoniumhydroxide; oxygen; (5-p-acetamidophenyl-10,15,20-triphenylporphinato)iron(III) chloride; In methanol; for 1h;

DOI:10.1016/S0040-4039(01)80886-8

upstream raw materials:

phenyl benzyl ketone

sodium ethanolate

styrene oxide

diethyl ether

Downstream raw materials:

β-phenyl-α-(trimethylsiloxy)ethylbenzene

phenyl benzyl ketone

1-benzoyl-1,2-diphenylethylene

(E)-1,2-diphenyl-ethene

Refernces

• 1、 Yus, Miguel,MacIá, Beatriz,Gómez, Cecilia,Soler, Tatiana,Falvello, Larry R.,Fanwick, Phillip E.. "Reductive ring opening of cis- and trans-2,3-diphenyloxirane: A common intermediate". . p. 3865 - 3871. Retrieved 2005.
• 2、 -. "INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION". Paragraph 00534-00536. . Retrieved 2021/10/15.
• 3、 Kandasamy, Jeyakumar,Lee, Yong Rok,Singh, Adesh Kumar,Venkatesh, Rapelly. "Palladium-catalyzed synthesis of α-aryl acetophenones from styryl ethers and aryl diazonium saltsviaregioselective Heck arylation at room temperature". supporting information. p. 7832 - 7837. Retrieved 2021/09/28.