angustione

Base Information

• Chemical Name: angustione
• CAS No.: 641-11-2
• Molecular Formula: C₁₁H₁₆O₃
• Molecular Weight: 196.246
• Mol file: 641-11-2.mol

Synonyms:Angustione

Chemical Property of angustione

Chemical Property:

• PSA: 51.21000
• LogP: 1.39580

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of angustione

There total 5 articles about angustione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic anhydride (108-24-7) → (+/-)-angustione (641-11-2,1206187-29-2)

Guidance literature:

With sodium acetate;

DOI:10.1039/jr9560002179 DOI:10.1039/jr9560004068 DOI:10.1039/jr9550002860

Reference yield:

→ (+/-)-angustione (641-11-2,1206187-29-2)

Guidance literature:

With palladium on activated charcoal; ethanol; Hydrogenation;

Reference yield:

trans-2-acetyl-4,6-dimethylcyclohexane-1,3-dione (134746-39-7,134780-48-6) → (+/-)-angustione (641-11-2,1206187-29-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / benzene / Heating; under azeotropic removal of water

In benzene;

DOI:10.1007/BF00601277

upstream raw materials:

4,4,6-trimethylcyclohexane-1,3-dione

acetyl chloride

trans-4,6-dimethyl-2-<1'-(N-pyrrolidyl)ethylidene>cyclohexane-1,3-dione

methyl iodide

Refernces

• 1、 Zenyuk, A. A.,Korchuk, A. V.,Ukhova, L. I.,Lis, G. L.. "SYNTHESIS OF (+/-)-ANGUSTIONE BY THE REGIOSELECTIVE ALKYLATION OF ENAMINODIKETONES UNDER THE ACTION OF STRONG BASES". . p. 519 - 524. Retrieved 2007/10/02.