Glycidyl Myristate

Base Information

• Chemical Name: Glycidyl Myristate
• CAS No.: 7460-80-2
• Molecular Formula: C₁₇H₃₂O₃
• Molecular Weight: 284.439
• Mol file: 7460-80-2.mol

Synonyms:Glycidyl Tetradecanoate;myristic acid-(2,3-epoxy-propyl ester);Myristic Acid Glycidyl Ester;Glycidyl Myristate;Myristinsaeureglycidester;tetradecanoyloxymethyl-oxirane;Myristinsaeure-(2,3-epoxy-propylester);

Chemical Property of Glycidyl Myristate

Chemical Property:

• Vapor Pressure: 1.45E-05mmHg at 25°C
• Boiling Point: 366.6°Cat760mmHg
• Flash Point: 142.6°C
• PSA: 38.83000
• Density: 0.948g/cm³
• LogP: 4.62950
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

GlycidylMyristate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Glycidyl Myristate is formed from monoacylglycerols and are present in edible fats and oils. A potential inhibitor of monoacylglycerol lipase.

Technology Process of Glycidyl Myristate

There total 5 articles about Glycidyl Myristate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

oxiranyl-methanol (556-52-5) + tetradecanoyl chloride (112-64-1) → oxiran-2-ylmethyl tetradecanoate (7460-80-2)

Guidance literature:

With triethylamine; In acetonitrile; at 0 - 20 ℃; for 12.5h; Inert atmosphere;

DOI:10.1002/chem.201904686

Reference yield:

allyl tetradecanoate (45236-96-2) → oxiran-2-ylmethyl tetradecanoate (7460-80-2)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 24h; Cooling with ice;

DOI:10.1007/s11746-011-1873-1

Reference yield:

n-tetradecanoic acid (544-63-8) → oxiran-2-ylmethyl tetradecanoate (7460-80-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Amberlyst 15 / toluene / 24 h / Reflux

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 24 h / 20 °C / Cooling with ice

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; toluene;

DOI:10.1007/s11746-011-1873-1

upstream raw materials:

sodium myristoate

epichlorohydrin

allyl tetradecanoate

n-tetradecanoic acid

Refernces

• 1、 Blumhorst, Michael R.,Venkitasubramanian, Padmesh,Collison, Mark W.. "Direct determination of glycidyl esters of fatty acids in vegetable Oils by LC-MS". experimental part. p. 1275 - 1283. Retrieved 2011/11/11.