2'',3'',5''-Triacetyl -azacytidine

Base Information

• Chemical Name: 2'',3'',5''-Triacetyl -azacytidine
• CAS No.: 10302-78-0
• Molecular Formula: C14H18 N4 O8
• Molecular Weight: 370.319
• Mol file: 10302-78-0.mol

Synonyms:s-Triazin-2(1H)-one,4-amino-1-b-D-ribofuranosyl-,2',3',5'-triacetate (7CI); s-Triazin-2(1H)-one, 4-amino-1-b-D-ribofuranosyl-, triacetate(ester) (8CI); NSC 291930

Chemical Property of 2'',3'',5''-Triacetyl -azacytidine

Chemical Property:

• Boiling Point: 497.3°Cat760mmHg
• PKA: 3.06±0.20(Predicted)
• Flash Point: 254.6°C
• PSA: 161.93000
• Density: 1.6g/cm³
• LogP: -0.87440
• Storage Temp.: Store at 0-5°C
• Solubility.: ≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide

Purity/Quality:

98%, ^*data from raw suppliers

5-Azacytidine2’,3’5’-O-triacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: 5-Azacytidine is an inhibitor of DNA methyltransferase, potentially serving to reverse epigenetic changes. It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes and cancer. 2’,3’,5’-triacetyl-5-Azacytidine is a prodrug form of 5-azacytidine that may be rapidly absorbed orally without formation of major metabolites in the gastrointestinal tract.
• Uses: 5-Azacytidine is an inhibitor of DNA methyltransferaes, potentially serving to reverse epigenetic changes. It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes and cancer. 2’,3’,5’-triacetyl-5-Azacytidine is a prodrug form of 5-azacytidine that may be rapidly absorbed orally without formation of major metabolites in the gastrointestinal tract.[Cayman Chemical]