2-AMINO-PYRIMIDINE-4-CARBOXYLIC ACID

Base Information

• Chemical Name: 2-AMINO-PYRIMIDINE-4-CARBOXYLIC ACID
• CAS No.: 2164-65-0
• Molecular Formula: C5H5N3O2
• Molecular Weight: 139.114
• Hs Code.: 29335990
• Mol file: 2164-65-0.mol

Synonyms:2-Aminopyrimidine-4-carboxylicacid;NSC 61555;

Chemical Property of 2-AMINO-PYRIMIDINE-4-CARBOXYLIC ACID

Chemical Property:

• Vapor Pressure: 8.19E-10mmHg at 25°C
• Melting Point: 285 °C
• Refractive Index: 1.663
• Boiling Point: 474.6 °C at 760 mmHg
• PKA: 1.55±0.10(Predicted)
• Flash Point: 240.8 °C
• PSA: 89.10000
• Density: 1.533g/cm³
• LogP: 0.33820
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Aminopyrimidine-4-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22
• Safety Statements: 24/25-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Description: 2-Aminopyrimidine-4-carboxylic acid is a natural product found in Gracilaria edulis, Gracilaria salicornia, and other organisms with data available.
• Uses: 2-Aminopyrimidine-4-carboxylic Acid is a substrate of the enzyme lathyrine synthase, and a precursor of the pyrimidine moiety of the non-protein amino acid lathyrine.

Technology Process of 2-AMINO-PYRIMIDINE-4-CARBOXYLIC ACID

There total 2 articles about 2-AMINO-PYRIMIDINE-4-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Amino-4-styryl-pyrimidin (125404-04-8) → 2-aminopyrimidine-4-carboxylic acid (2164-65-0)

Guidance literature:

With potassium permanganate;

Reference yield:

→ 2-aminopyrimidine-4-carboxylic acid (2164-65-0)

Guidance literature:

2-Amino-4-methyl-pyrimidin, verd. wss. KMnO4-Lsg.;

Reference yield: 50.0%

2-aminopyrimidine-4-carboxylic acid (2164-65-0) + 4-methoxy-aniline (104-94-9) → 2-aminopyrimidine-4-carboxy-(4-methoxyphenyl)amide (1001326-15-3)

Guidance literature:

With benzotriazol-1-ol; triethylamine; dmap; In N,N-dimethyl-formamide; at 20 ℃; for 44h;

DOI:10.1021/jm070852a

upstream raw materials:

2-Amino-4-styryl-pyrimidin

Downstream raw materials:

2-aminopyrimidine-4-carboxy-(4-methoxyphenyl)amide

2-amino-pyrimidine-4-carboxylic acid {4-[1-(4-chloro-benzyl)-4-oxo-1,4-dihydro-thieno[3,2-d]pyrimidin-6-yl]-phenyl}-amide