Temephos

Base Information

• Chemical Name: Temephos
• CAS No.: 3383-96-8
• Deprecated CAS: 53320-58-4
• Molecular Formula: C16H20O6P2S3
• Molecular Weight: 466.477
• Hs Code.: 2930909061
• European Community (EC) Number: 222-191-1
• ICSC Number: 0199
• NSC Number: 755842
• UN Number: 3077,2783
• UNII: ONP3ME32DL
• DSSTox Substance ID: DTXSID1032484
• Nikkaji Number: J4.517I
• Wikipedia: Temefos
• Wikidata: Q417958
• NCI Thesaurus Code: C80606
• Metabolomics Workbench ID: 56089
• ChEMBL ID: CHEMBL1355821
• Mol file: 3383-96-8.mol

Synonyms:Abate;Difos;Temefos;Temephos

Chemical Property of Temephos

Chemical Property:

• Appearance/Colour: White crystalline solid or liquid.
• Vapor Pressure: 2.44E-10mmHg at 25°C
• Melting Point: 30-31 °C
• Refractive Index: 1.612
• Boiling Point: 518.5 °C at 760 mmHg
• Flash Point: 267.4 °C
• PSA: 164.48000
• Density: 1.4 g/cm³
• LogP: 6.93120
• Storage Temp.: 2-8°C
• Water Solubility.: 0.003 g/100 mL
• XLogP3: 6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 10
• Exact Mass: 465.98972587
• Heavy Atom Count: 27
• Complexity: 474
• Transport DOT Label: Class 9

Purity/Quality:

90%TC 50%EC 1%SG ^*data from raw suppliers

Temephos ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn, N
• Hazard Codes: Xn,N
• Statements: 21/22-51/53
• Safety Statements: 22-37-61-60

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Pesticides -> Organophosphate Insecticides
• Canonical SMILES: COP(=S)(OC)OC1=CC=C(C=C1)SC2=CC=C(C=C2)OP(=S)(OC)OC
• Inhalation Risk: A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20 °C.
• Effects of Short Term Exposure: Cholinesterase inhibition. The substance may cause effects on the nervous system. This may result in convulsions and respiratory depression. The effects may be delayed. Medical observation is indicated. Exposure far above the OEL could cause death.
• Effects of Long Term Exposure: Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
• Description: Abate is the trade name for Temephos, the known organophosphate larvicide. Abate is used to treat water infested with disease-carrying fleas and control mosquito, midge, and black fly larvae. Abate quickly controls mosquito and other insect populations because it kills insect larvae before they mature, and the residual activity of abate prevents insect populations. On decomposition, abate produces oxides of carbon, phosphorous, and sulphur. Exposures to abate in workplaces cause adverse health effects (refer to Temephos for details).
• Uses: Temephos is an organophosphate larvicide used to treat water infested with disease-carrying insects. Temephos is used to control mosquito and black fly larvae in aqueous environments and as a human and veterinary ectoparasiticide.

Technology Process of Temephos

There total 2 articles about Temephos which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4'-Thiodiphenol (2664-63-3) + dimethyl chlorothiophosphate (2524-03-0) → temephos (3383-96-8)

Guidance literature:

With sodium methylate; In chloroform; butanone;

Reference yield:

→ temephos (3383-96-8)

Guidance literature:

entspr. Phenol, P-Cl-Verb.;

upstream raw materials:

4,4'-Thiodiphenol

dimethyl chlorothiophosphate

Refernces

• 1、 -. "Pesticide compositions and method". . . Retrieved 2008/06/13.