1-benzyl-1-(4-methoxyphenyl)hydrazine Hydrochloride

Base Information

• Chemical Name: 1-benzyl-1-(4-methoxyphenyl)hydrazine Hydrochloride
• CAS No.: 5705-10-2
• Molecular Formula: C₁₄H₁₆N₂O*ClH
• Molecular Weight: 264.755
• NSC Number: 405605
• DSSTox Substance ID: DTXSID90385151
• Mol file: 5705-10-2.mol

Synonyms:1-benzyl-1-(4-methoxyphenyl)hydrazine Hydrochloride;5705-10-2;1-benzyl-1-(4-methoxyphenyl)hydrazine;hydrochloride;AC1MCXK5;Cambridge id 5107578;SCHEMBL9737798;DTXSID90385151;NSC405605;NSC-405605;SR-01000195473;a-benzyl-a-(p-methoxyphenyl)-hydrazine hydrochloride;SR-01000195473-1

Chemical Property of 1-benzyl-1-(4-methoxyphenyl)hydrazine Hydrochloride

Chemical Property:

• Vapor Pressure: 1.48E-06mmHg at 25°C
• Boiling Point: 398.4°Cat760mmHg
• Flash Point: 194.7°C
• Density: 1.145g/cm³
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 264.1029409
• Heavy Atom Count: 18
• Complexity: 208

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)N(CC2=CC=CC=C2)N.Cl

Technology Process of 1-benzyl-1-(4-methoxyphenyl)hydrazine Hydrochloride

There total 1 articles about 1-benzyl-1-(4-methoxyphenyl)hydrazine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl chloride (100-44-7) + 4-Methoxyphenylhydrazine (3471-32-7) → N-benzyl-N-(4-methoxy-phenyl)-hydrazine; hydrochloride (5705-10-2)

Guidance literature:

DOI:10.1021/ja01621a042

Reference yield: 80.0%

diethyl (3-oxopropyl)phosphonate (3986-95-6) + N-benzyl-N-(4-methoxy-phenyl)-hydrazine; hydrochloride (5705-10-2) → (1-Benzyl-5-methoxy-1H-indol-3-ylmethyl)-phosphonic acid diethyl ester (119592-34-6)

Guidance literature:

In ethanol; Heating;

Reference yield:

N-benzyl-N-(4-methoxy-phenyl)-hydrazine; hydrochloride (5705-10-2) → 2-(1-benzyl-5-methoxy-2-methyl-indol-3-yl)-ethylamine (441-91-8)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous NaOH; acetic acid / Erwaermen des Reaktionsprodukts mit aethanol. HCl und Behandeln des erhaltenen Esters mit wss.-aethanol. NaOH

2: 190 °C

3: LiAlH₄; diethyl ether

With sodium hydroxide; lithium aluminium tetrahydride; diethyl ether; acetic acid;

DOI:10.1021/ja01621a042

upstream raw materials:

benzyl chloride

4-Methoxyphenylhydrazine

Downstream raw materials:

5-methoxy-2-methyl-1-(phenylmethyl)-1H-indol-3-ylacetic acid

2-(2-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)ethyl)isoindoline-1,3-dione

(1-Benzyl-5-methoxy-1H-indol-3-ylmethyl)-phosphonic acid diethyl ester

2-(1-benzyl-5-methoxy-2-methyl-indol-3-yl)-ethylamine