N-sec-butylaniline

Base Information

• Chemical Name: N-sec-butylaniline
• CAS No.: 6068-69-5
• Molecular Formula: C10H15N
• Molecular Weight: 149.2328
• Hs Code.: 2921420090
• Mol file: 6068-69-5.mol

Synonyms:Benzenamine, N-(1-methylpropyl)-;N-sec-Butylaniline;Aniline,N-sec-butyl;

Chemical Property of N-sec-butylaniline

Chemical Property:

• Vapor Pressure: 0.0885mmHg at 25°C
• Melting Point: 1.08°C (estimate)
• Refractive Index: 1.5333
• Boiling Point: 225°Cat760mmHg
• Flash Point: 93.3°C
• PSA: 12.03000
• Density: 0.939g/cm³
• LogP: 2.97000

Purity/Quality:

99% ^*data from raw suppliers

N-SEC-BUTYLANILINE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-sec-butylaniline

There total 30 articles about N-sec-butylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

aniline (62-53-3) + iso-butanol (78-92-2,15892-23-6) → N-sec-butyl-aniline (881008-34-0,6068-69-5)

Guidance literature:

With [Zr₆O₄(OH)4]⁽¹²⁺⁾*5.7C₈H₅NO₄^(2-)*0.3C₁₃H₂₀N₂O*0.3Ir⁽¹⁺⁾; hydrogen; at 80 ℃; for 24h; under 4500.45 Torr; Autoclave; Green chemistry;

DOI:10.1002/cctc.201402101

Reference yield: 100.0%

aniline (62-53-3) + butanone (78-93-3) → N-sec-butyl-aniline (881008-34-0,6068-69-5)

Guidance literature:

With iridium bromide; formic acid; zinc; In water; at 30 ℃; for 20h;

DOI:10.1016/j.tetlet.2009.11.107

Reference yield: 99.0%

SEC-BUTYLAMINE (33966-50-6) + chlorobenzene (108-90-7) → N-sec-butyl-aniline (881008-34-0,6068-69-5)

Guidance literature:

With (R)-(-)-1-[(S)-2-(dicyclohexylphosphino)ferrocenyl]ethyl di-t-butylphosphine; sodium t-butanolate; palladium diacetate; In 1,2-dimethoxyethane; at 100 ℃; for 48h;

DOI:10.1002/anie.200462629

upstream raw materials:

nitrobenzene

butanone

s-butyl chloride

aniline

Downstream raw materials:

1-sec-Butyl-1-phenyl-3-phenylacetyl-thiourea

1-(1-methylpropyl)-1-phenylhydrazine

N-sec-Butyl-N-alkyl-3,4-dichlorbenzamid

C₁₁H₁₄ClNO

Refernces

• 1、 Homberg, Leonard,Roller, Alexander,Hultzsch, Kai C.. "A Highly Active PN3 Manganese Pincer Complex Performing N-Alkylation of Amines under Mild Conditions". supporting information. . Retrieved 2019/05/07.
• 2、 Bayguzina,Musina, Ch. F.,Khusnutdinov. "N-Alkylation of Aniline and Its Derivatives by Alcohols in the Presence of Copper Compounds". . p. 1652 - 1659. Retrieved 2019/02/12.