N-(5-Guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)benzamide hydrochloride

Base Information

• Chemical Name: N-(5-Guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)benzamide hydrochloride
• CAS No.: 911-77-3
• Molecular Formula: C19H22N6O4^.HCl
• Molecular Weight: 434.882
• Hs Code.: 29252900
• European Community (EC) Number: 213-011-2
• DSSTox Substance ID: DTXSID50883603
• ChEMBL ID: CHEMBL1898160
• Mol file: 911-77-3.mol

Synonyms:BAPNA;Benzoylarginine Nitroanilide;Benzoylarginine Nitroanilide Monohydrochloride;Benzoylarginine Nitroanilide, (R)-Isomer;Benzoylarginine Nitroanilide, (S)-Isomer;Benzoylarginine Nitroanilide, Monosodium Salt, Monohydrochloride;Monohydrochloride, Benzoylarginine Nitroanilide;N alpha Benzoyl DL arginine 4 nitroanilide;N Benzoylarginine 4 nitroanilide;N Benzoylarginyl 4 nitroanilide;N-alpha-Benzoyl-DL-arginine-4-nitroanilide;N-Benzoylarginine-4-nitroanilide;N-Benzoylarginyl-4-nitroanilide;Nitroanilide, Benzoylarginine

Chemical Property of N-(5-Guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)benzamide hydrochloride

Chemical Property:

• Appearance/Colour: Light yellow fine crystalline powder
• Melting Point: ~275 °C (dec.)
• PSA: 165.92000
• Density: 1.37 g/cm³
• LogP: 4.57520
• Storage Temp.: −20°C
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 434.1469309
• Heavy Atom Count: 30
• Complexity: 588

Purity/Quality:

99% ^*data from raw suppliers

N-Benzoyl-DL-arginine 4-nitroanilide hydrochloride ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NC(CCCN=C(N)N)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-].Cl
• Uses: Substrate for trypsin, papain, ficin, bromelain, plasmin, and cathepsin B. Nα-Benzoyl-DL-arginine 4-nitroanilide hydrochloride has been used as a substrate for trypsin and elastase in enzyme analysis.

Technology Process of N-(5-Guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)benzamide hydrochloride

There total 1 articles about N-(5-Guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)benzamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ alpha-N-benzoyl-DL-arginine-p-nitroanilide hydrochloride (911-77-3,21653-40-7)

Guidance literature:

N^α-Benzoyl-N^ω-nitro-DL-arginin-p-nitroanilid;

DOI:10.1246/bcsj.43.2900

Reference yield:

alpha-N-benzoyl-DL-arginine-p-nitroanilide hydrochloride (911-77-3,21653-40-7) → 2-Benzoylamino-5-guanidino-pentanoic acid; hydrochloride (125652-40-6) + 4-nitro-aniline (100-01-6,104810-17-5)

Guidance literature:

With water; papain; In tetrahydrofuran; var. enzymes;

DOI:10.1021/ja00009a016

Reference yield:

alpha-N-benzoyl-DL-arginine-p-nitroanilide hydrochloride (911-77-3,21653-40-7) → N-α-benzoyl-DL-arginine (6453-58-3) + 4-nitro-aniline (100-01-6,104810-17-5)

Guidance literature:

With water; Reagent/catalyst; Temperature; Kinetics; HEPES buffer; Enzymatic reaction;

DOI:10.3762/bjoc.6.98

Downstream raw materials:

2-Benzoylamino-5-guanidino-pentanoic acid; hydrochloride

4-nitro-aniline

N-α-benzoyl-DL-arginine