7-Methylpteridine-2,4-diamine

Base Information

• Chemical Name: 7-Methylpteridine-2,4-diamine
• CAS No.: 4215-07-0
• Molecular Formula: C7H8N6
• Molecular Weight: 176.181
• Hs Code.: 2933990090
• NSC Number: 78958
• DSSTox Substance ID: DTXSID40291894
• Wikidata: Q82029982
• Mol file: 4215-07-0.mol

Synonyms:7-methylpteridine-2,4-diamine;4215-07-0;NSC78958;Oprea1_162507;2,4-Diamino-7-methylpteridine;7-methyl-2,4-diaminopteridine;DTXSID40291894;CECXILQSXHHKTG-UHFFFAOYSA-N;7-Methyl-2,4-pteridinediamine #;NSC-78958;AKOS006278524;2,4-Pteridinediamine,7-methyl-(9CI);CS-0452423;EN300-132575

Chemical Property of 7-Methylpteridine-2,4-diamine

Chemical Property:

• Vapor Pressure: 2.34E-09mmHg at 25°C
• Refractive Index: 1.791
• Boiling Point: 479.5 °C at 760 mmHg
• Flash Point: 275.4 °C
• PSA: 103.60000
• Density: 1.502 g/cm³
• LogP: 1.05500
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 176.08104428
• Heavy Atom Count: 13
• Complexity: 186

Purity/Quality:

99% ^*data from raw suppliers

7-METHYL-2,4-PTERIDINEDIAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CN=C2C(=NC(=NC2=N1)N)N

Technology Process of 7-Methylpteridine-2,4-diamine

There total 22 articles about 7-Methylpteridine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1-butylsulfanylpropan-2-one (79948-21-3) + 2,4,5,6-tetraaminopyrimidine sulfate (5392-28-9,49647-58-7) → 7-methyl-2,4-diaminopteridine (4215-07-0)

Guidance literature:

With piperidine; In water; at 20 ℃; for 268h;

DOI:10.1007/BF00952940

Reference yield: 86.0%

2,4,5,6-tetraaminopyrimidine sulfate (5392-28-9,49647-58-7) + 1-chloro-1-benzamidoacetone (88297-80-7) → 7-methyl-2,4-diaminopteridine (4215-07-0)

Guidance literature:

With piperidine; In water; at 20 ℃; for 168h;

DOI:10.1007/BF00956526

Reference yield: 82.0%

2,4,5,6-tetraaminopyrimidine (1004-74-6) + benzamidoacetone (50996-03-7) → 7-methyl-2,4-diaminopteridine (4215-07-0)

Guidance literature:

With piperidine; In water; at 20 ℃; for 150h;

DOI:10.1007/BF01094658

upstream raw materials:

2,4,5,6-tetraaminopyrimidine

2-oxopropanal

benzamidoacetone

1-(benzenesulfonyl)-4-methylimidazolin-2-one

Downstream raw materials:

2-amino-1,4-dihydro-4-oxopteridine-7-carboxylic acid

7-methylpterin

2-amino-6-methylpyrazine-3-carboxylic acid

Refernces

• 1、 Zav'yalov, S. I.,Zavoshin, A. G.. "SYNTHESIS OF SUBSTITUTED PTERIDINES". . p. 419 - 422. Retrieved 2007/10/02.
• 2、 Zav'yalov, S. I.,Zavolin, A. G.. "REACTION OF TETRAAMINOPYRIMIDINE WITH 1-ARYLSULFONYL-4-METHYLIMIDAZOLIN-2-ONES". . p. 1700 - 1703. Retrieved 2007/10/02.