2-amino-N-ethylacetamide

Base Information

• Chemical Name: 2-amino-N-ethylacetamide
• CAS No.: 62029-79-2
• Molecular Formula: C4H11N2O
• Molecular Weight: 102.136
• European Community (EC) Number: 823-026-1
• UNII: 812L8B539W
• Mol file: 62029-79-2.mol

Synonyms:2-amino-N-ethylacetamide;62029-79-2;n-ethylglycinamide;Acetamide, 2-amino-N-ethyl-;812L8B539W;2-amino-N-ethyl-acetamide;glycine ethylamide;SCHEMBL1536829;UNII-812L8B539W;QCQZFSUBYDWVBG-UHFFFAOYSA-N;MFCD06655350;AKOS000206342;BS-12685;BB 0259530;CS-0213253;FT-0727730;EN300-12567;E79648;AS-787/43399854;Z54747476

Chemical Property of 2-amino-N-ethylacetamide

Chemical Property:

• Vapor Pressure: 0.00757mmHg at 25°C
• Melting Point: 17-19 °C (decomp)
• Boiling Point: 268.7 °C at 760 mmHg
• PKA: 15.38±0.46(Predicted)
• Flash Point: 116.3 °C
• Density: 0.980±0.06 g/cm3(Predicted)
• XLogP3: -1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 102.079312947
• Heavy Atom Count: 7
• Complexity: 62.7

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-n-ethylacetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCNC(=O)CN

Technology Process of 2-amino-N-ethylacetamide

There total 6 articles about 2-amino-N-ethylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzyl N-[2-(ethylamino)-2-oxoethyl]carbamate (21855-73-2) → 2-amino-N-ethyl-acetamide (62029-79-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 12.5h;

DOI:10.1016/S0968-0896(01)00201-2

Reference yield:

glycylalanine (926-77-2,2325-50-0) → acetamide (60-35-5) + 2-amino-N-ethyl-acetamide (62029-79-2) + acetaldehyde (75-07-0,9002-91-9) + 2-Amino-N-[2-(2-amino-acetylamino)-1-methyl-propyl]-acetamide

Guidance literature:

With water; Product distribution; Mechanism; Irradiation; var. pH, also for glycylglycine;

Reference yield:

2-chloro-N-ethylacetamide (105-35-1) → 2-amino-N-ethyl-acetamide (62029-79-2)

Guidance literature:

With methanol; ammonia; at 100 ℃; im Rohr;

upstream raw materials:

2-chloro-N-ethylacetamide

glycine ethyl ester hydrochloride

ethylamine

glycylalanine

Downstream raw materials:

[1-benzyl-3-(ethylcarbamoylmethyl-carbamoyl)-3,3-difluoro-2-hydroxy-propyl]-carbamic acid benzyl ester

2-[1-(3,4-Dimethoxy-benzyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-N-ethylcarbamoylmethyl-2-phenyl-acetamide

2-({2-chloro-4-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-N-hydroxy-benzimidoyl}-amino)-N-ethyl-acetamide

N-ethyl-2-({N-hydroxy-2-methyl-4-[5-trifluoromethyl-5-(3-trifluoromethyl-phenyl)-4,5-dihydro-isoxazol-3-yl]-benzimidoyl}-amino)-acetamide

Refernces

• 1、 Harada,Asano,Kawata,Inoue,Horizoe,Yasuda,Nagata,Murakami,Nagaoka,Kobayashi,Tanaka,Abe. "2-Alkynyl-8-aryladenines possessing an amide moiety: Their synthesis and structure-activity relationships of effects on hepatic glucose production induced via agonism of the A2B adenosine receptor". . p. 2709 - 2726. Retrieved 2007/10/03.