Isosakuranetin-7-neohesperidoside

Base Information

• Chemical Name: Isosakuranetin-7-neohesperidoside
• CAS No.: 14941-08-3
• Molecular Formula: C28H34O14
• Molecular Weight: 594.57
• Hs Code.: 29389090
• European Community (EC) Number: 239-020-1
• Wikipedia: Poncirin
• Mol file: 14941-08-3.mol

Synonyms:poncirin

Chemical Property of Isosakuranetin-7-neohesperidoside

Chemical Property:

• Vapor Pressure: 7.27E-35mmHg at 25°C
• Melting Point: 210 °C
• Refractive Index: 1.677
• Boiling Point: 900.1 °C at 760 mmHg
• PKA: 7.15±0.40(Predicted)
• Flash Point: 296.5 °C
• PSA: 214.06000
• Density: 1.596 g/cm³
• LogP: -0.86220
• XLogP3: -0.2
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 14
• Rotatable Bond Count: 7
• Exact Mass: 594.19485575
• Heavy Atom Count: 42
• Complexity: 900

Purity/Quality:

99%, ^*data from raw suppliers

Poncirin ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(C=C5)OC)O)CO)O)O)O)O)O
• Uses: Poncirin is a natural bitter flavanone glycoside present in many species of citrus fruits which has various biological benefits such as antioxidant, antimicrobial, anti-inflammatory and anti-cancer activities. Main constituent used in traditional Chinese medicine for inflammation, asthma, and infection diseases.

Technology Process of Isosakuranetin-7-neohesperidoside

There total 4 articles about Isosakuranetin-7-neohesperidoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

poncirin chalcone (23643-72-3) → poncirin (14941-08-3)

Guidance literature:

With pyridine; In water; Ambient temperature;

DOI:10.1016/0031-9422(81)85111-4

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → poncirin (14941-08-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 340 mg / 25 percent KOH / ethanol

2: 160 mg / pyridine / H₂O / Ambient temperature

With pyridine; potassium hydroxide; In ethanol; water;

DOI:10.1016/0031-9422(81)85111-4

Reference yield:

2,6-dihydroxy-4-(β-neohesperidosyloxy)acetophenone (23643-71-2) → poncirin (14941-08-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 340 mg / 25 percent KOH / ethanol

2: 160 mg / pyridine / H₂O / Ambient temperature

With pyridine; potassium hydroxide; In ethanol; water;

DOI:10.1016/0031-9422(81)85111-4

upstream raw materials:

poncirin chalcone

4-methoxy-benzaldehyde

2,6-dihydroxy-4-(β-neohesperidosyloxy)acetophenone

Refernces