2,4-Dichloro-1,3,5-triazine

Base Information

• Chemical Name: 2,4-Dichloro-1,3,5-triazine
• CAS No.: 2831-66-5
• Molecular Formula: C3HCl2N3
• Molecular Weight: 149.967
• Hs Code.: 2933699090
• European Community (EC) Number: 676-236-9
• DSSTox Substance ID: DTXSID10274598
• Nikkaji Number: J1.553.128B
• Wikidata: Q72468412
• Mol file: 2831-66-5.mol

Synonyms:2,4-Dichloro-1,3,5-triazine;2831-66-5;dichloro-s-triazine;1,3,5-TRIAZINE, 2,4-DICHLORO-;MFCD04115347;C3HCl2N3;2,4-dichloro-[1,3,5]triazine;SCHEMBL32909;2,6-dichloro-1,3,5-triazine;2.4-dichloro-1,3,5-triazine;DTXSID10274598;2,4-dichlor-[1,3,5]triazine;BCP22466;2,4-Dichloro-[1,3,5]-triazine;BBL103328;STL557138;2, 4-dichloro-1, 3, 5-triazine;AKOS005259807;AC-2953;CS-T-17746;PB20114;PS-4865;SY003416;A5385;AM20090359;CS-0052169;D4891;FT-0645176;EN300-98635;J-507110;Z1201622881

Chemical Property of 2,4-Dichloro-1,3,5-triazine

Chemical Property:

• Vapor Pressure: 0.00034mmHg at 25°C
• Melting Point: 54.0 to 58.0 °C
• Refractive Index: 1.565
• Boiling Point: 329.444 °C at 760 mmHg
• PKA: -1.24±0.10(Predicted)
• Flash Point: 183.078 °C
• PSA: 38.67000
• Density: 1.612 g/cm³
• LogP: 1.17840
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 148.9547524
• Heavy Atom Count: 8
• Complexity: 70.9

Purity/Quality:

99% ^*data from raw suppliers

2,4-Dichloro-1,3,5-triazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=NC(=NC(=N1)Cl)Cl
• Uses: 2,4-Dichloro-1,3,5-triazine is used as an intermediate in organic synthesis and pharmaceutical intermediates, and it is an intermediate in the preparation of bromhexine impurities.

Technology Process of 2,4-Dichloro-1,3,5-triazine

There total 8 articles about 2,4-Dichloro-1,3,5-triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

1,3,5-Triazine (290-87-9) → 2,4-dichloro-1,3,5-triazine (2831-66-5) + 1,3,5-trichloro-2,4,6-triazine (108-77-0)

Guidance literature:

With chlorine; In tetrachloromethane; in closed tube at 140-200°C;

DOI:10.1021/ja01606a015

Reference yield:

C.I. reactive red 2 → 2,4-dichloro-1,3,5-triazine (2831-66-5) + sodium 3,5-diamino-4-hydroxynaphthalene-2,7-disulfonate + aniline (62-53-3)

Guidance literature:

With hydrogenchloride; In water; at 30 ℃; pH=1; pH-value; Temperature;

DOI:10.1016/j.inoche.2020.107969

Reference yield:

cyanogen chloride (506-77-4) → 2,4-dichloro-1,3,5-triazine (2831-66-5) + 1,3,5-trichloro-2,4,6-triazine (108-77-0)

Guidance literature:

With hydrogenchloride; hydrogen cyanide;

DOI:10.1021/ja01640a051

upstream raw materials:

cyanogen chloride

1,3,5-Triazine

tetrachloromethane

chlorine

Downstream raw materials:

N²,N⁴-diphenyl-2,4-triazinediamine

C₁₅H₁₃ClN₄

4-chloro-N-(4-chlorophenyl)-1,3,5-triazin-2-amine

4-chloro-N-[2-(methanesulfonyl)phenyl]-1,3,5-triazin-2-amine

Refernces