Phenylglyoxal-bisphenylhydrazon

Base Information

• Chemical Name: Phenylglyoxal-bisphenylhydrazon
• CAS No.: 7397-17-3
• Molecular Formula: C20H18 N4
• Molecular Weight: 314.39
• NSC Number: 146218
• Mol file: 7397-17-3.mol

Synonyms:NSC146218;Phenylglyoxal-bisphenylhydrazon;7397-17-3;NSC-146218

Chemical Property of Phenylglyoxal-bisphenylhydrazon

Chemical Property:

• Boiling Point: 471.7°Cat760mmHg
• Flash Point: 239°C
• Density: 1.09g/cm³
• XLogP3: 5.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 314.153146591
• Heavy Atom Count: 24
• Complexity: 400

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=NNC2=CC=CC=C2)C=NNC3=CC=CC=C3
• Isomeric SMILES: C1=CC=C(C=C1)/C(=N/NC2=CC=CC=C2)/C=N/NC3=CC=CC=C3

Technology Process of Phenylglyoxal-bisphenylhydrazon

There total 27 articles about Phenylglyoxal-bisphenylhydrazon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

phenylglyoxal hydrate (1074-12-0) + phenylhydrazine (100-63-0) → phenylglyoxal oxazone (7397-17-3)

Guidance literature:

In acetic acid; for 0.5h; Heating;

Reference yield: 70.0%

5-Chloro-2-phenyl-1-oxa-4-aza-3a-azonia-indene; perchlorate → (6-Chloro-pyridazin-3-yl)-phenyl-diazene (83407-23-2) + N-(6-Chloro-pyridazin-3-yl)-N'-phenyl-hydrazine (83407-26-5) + phenylglyoxal oxazone (7397-17-3)

Guidance literature:

With phenylhydrazine; In acetonitrile; for 20h; Heating;

Reference yield: 63.0%

2,2-dibromoacetophenone (13665-04-8) + phenylhydrazine (100-63-0) → phenylglyoxal oxazone (7397-17-3)

Guidance literature:

In ethanol; for 3h; Solvent; Reflux;

upstream raw materials:

phenylglyoxal hydrate

phenylhydrazine acetate

phenylhydrazine hydrochloride

acetic acid

Downstream raw materials:

(1E,2E)-1,2-diphenylethane-1,2-dione bis(phenylhydrazone)

α-(N'-phenyl-hydrazino)-deoxybenzoin-phenylhydrazone

benzil bisphenylhydrazone

Refernces

• 1、 Satoh, Kazue,Miyasaka, Tadashi,Arakawa, Kiichi. "Studies on Heterocyclic Compounds. XX. The Reaction of the Oxazolopyridazinium Perchlorates with Hydrazines". . p. 1557 - 1566. Retrieved 2007/10/02.