4,4-Diphenylbutan-1-ol

Base Information

• Chemical Name: 4,4-Diphenylbutan-1-ol
• CAS No.: 56740-71-7
• Molecular Formula: C16H18 O
• Molecular Weight: 226.318
• European Community (EC) Number: 260-360-1
• DSSTox Substance ID: DTXSID50205301
• Nikkaji Number: J267.100J
• Wikidata: Q83078844
• Mol file: 56740-71-7.mol

Synonyms:4,4-Diphenylbutan-1-ol;56740-71-7;EINECS 260-360-1;4,4-Diphenyl-1-butanol;4,4-Dipenyl-1-butanol;4,4-diphenylbutane-1-ol;SCHEMBL4575392;DTXSID50205301

Chemical Property of 4,4-Diphenylbutan-1-ol

Chemical Property:

• Vapor Pressure: 2.57E-06mmHg at 25°C
• Refractive Index: 1.569
• Boiling Point: 375.8°C at 760 mmHg
• Flash Point: 155.9°C
• PSA: 20.23000
• Density: 1.044g/cm³
• LogP: 3.59100
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 226.135765193
• Heavy Atom Count: 17
• Complexity: 172

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(CCCO)C2=CC=CC=C2

Technology Process of 4,4-Diphenylbutan-1-ol

There total 27 articles about 4,4-Diphenylbutan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1,1-diphenylbutan-1,4-diol (1023-94-5) → 4,4-diphenyl-1-butanol (56740-71-7)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethyl acetate; for 8h;

DOI:10.1039/c9cc04287c

Reference yield: 92.0%

Acetic acid 4,4-diphenyl-butyl ester → 4,4-diphenyl-1-butanol (56740-71-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 4h; Heating;

Reference yield: 90.0%

ethyl 4,4-diphenylbutanoate (10347-28-1) → 4,4-diphenyl-1-butanol (56740-71-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 5h; Heating;

DOI:10.1021/jm00149a014

upstream raw materials:

4,4-diphenylbutanoic acid

trimethylene oxide

diphenylmethyllithium

methyl 4,4-diphenylbutanoate

Downstream raw materials:

4-methanesulfonyloxy-1,1-diphenylbutane

4-(4,4-diphenyl-butyl)-piperazine-1-carboxylic acid ethyl ester

1-(4,4-diphenylbutyl)piperazine

C₂₃H₃₀N₂O₅

Refernces

• 1、 Pandey, Ganesh,Laha, Ramkrishna,Mondal, Pradip Kumar. "Heterocyclization involving benzylic C(sp3)-H functionalization enabled by visible light photoredox catalysis". supporting information. p. 9689 - 9692. Retrieved 2019/08/15.
• 2、 Schmidt, Matthias,Ungvari, Johannes,Gloede, Julia,Dobner, Bodo,Langner, Andreas. "New 1,3-dioxolane and 1,3-dioxane derivatives as effective modulators to overcome multidrug resistance". . p. 2283 - 2297. Retrieved 2007/10/03.