2-METHOXY-5-METHYLBENZALDEHYDE

Base Information

• Chemical Name: 2-METHOXY-5-METHYLBENZALDEHYDE
• CAS No.: 7083-19-4
• Molecular Formula: C9H10O2
• Molecular Weight: 150.177
• Hs Code.: 2912499000
• Mol file: 7083-19-4.mol

Synonyms:2-formyl-4-methylanisole;2-Methoxy-4-methylbenzaldehyd;5-Methyl-2-methoxy-benzaldehyd;2-Methoxy-5-methyl-benzaldehyde;2-Methoxy-5-methyl-benzaldehyd;

Chemical Property of 2-METHOXY-5-METHYLBENZALDEHYDE

Chemical Property:

• Vapor Pressure: 0.0192mmHg at 25°C
• Boiling Point: 252.6°C at 760 mmHg
• Flash Point: 110.4°C
• PSA: 26.30000
• Density: 1.08
• LogP: 1.81610
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

2-Methoxy-5-methylbenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHOXY-5-METHYLBENZALDEHYDE

There total 13 articles about 2-METHOXY-5-METHYLBENZALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-hydroxy-5-methylbenzaldehyde (613-84-3) + methyl iodide (74-88-4) → 2-methoxy-5-methylbenzaldehyde (7083-19-4)

Guidance literature:

With potassium carbonate;

DOI:10.1139/v2012-069

Reference yield: 77.0%

(2-methoxy-5-methylphenyl)methanol (7048-40-0) → 2-methoxy-5-methylbenzaldehyde (7083-19-4)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; for 1h; Ambient temperature;

Reference yield: 60.0%

p-methylanizole (104-93-8) + Dichloromethyl methyl ether (4885-02-3) → 2-methoxy-5-methylbenzaldehyde (7083-19-4)

Guidance literature:

With silver trifluoromethanesulfonate; In dichloromethane; at -78 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1021/jo400056k

upstream raw materials:

p-methylanizole

hydrogen cyanide

N,N-dimethyl-formamide

2-hydroxy-5-methylbenzaldehyde

Downstream raw materials:

4-methyl-2-(trans-2-nitro-vinyl)-anisole

(E)-3-(2-methoxy-5-methylphenyl)propenoic acid

(2-methoxy-5-methyl-benzyliden)-aniline

1-(2'-methoxy-5'-methylphenyl)-2-methylpropan-1-ol

Refernces

• 1、 Dickschat, Jeroen S.,Wang, Tao,Stadler, Marc. "Volatiles from the xylarialean fungus Hypoxylon invadens". . p. 734 - 746. Retrieved 2018/04/16.
• 2、 Ohsawa, Kosuke,Yoshida, Masahito,Doi, Takayuki. "A direct and mild formylation method for substituted benzenes utilizing dichloromethyl methyl ether-silver trifluoromethanesulfonate". . p. 3438 - 3444. Retrieved 2013/06/26.