MECOPROP METHYL ESTER

Base Information

• Chemical Name: MECOPROP METHYL ESTER
• CAS No.: 23844-56-6
• Molecular Formula: C11H13 Cl O3
• Molecular Weight: 228.675
• Hs Code.: 2918990090
• Mol file: 23844-56-6.mol

Synonyms:Propanoicacid, 2-(4-chloro-2-methylphenoxy)-, methyl ester, (?à)-; Propionic acid, 2-[(4-chloro-o-tolyl)oxy]-, methylester, (?à)- (8CI); (?à)-Mecoprop methyl ester;2-(2-Methyl-4-chlorophenoxy)propionic acid methyl ester; MCPP methyl ester;Mecoprop methyl ester

Chemical Property of MECOPROP METHYL ESTER

Chemical Property:

• Vapor Pressure: 0.005mmHg at 25°C
• Boiling Point: 294.2 °C at 760 mmHg
• Flash Point: 115.1 °C
• PSA: 35.53000
• Density: 1.172 g/cm³
• LogP: 2.58870

Purity/Quality:

98% ^*data from raw suppliers

MCPPMethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: MCPP Methyl Ester is a pesticide residue analyzed in foodstuffs.

Technology Process of MECOPROP METHYL ESTER

There total 2 articles about MECOPROP METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Methyl 2-bromopropionate (5445-17-0) + 2-methyl-4-chlorophenol (1570-64-5) → methyl R-2-(4-chloro-2-methylphenoxy)propanoate (23844-56-6,2786-19-8)

Guidance literature:

With tetrabutylammomium bromide; potassium carbonate; In toluene; at 99.84 ℃;

DOI:10.1007/s12039-017-1368-1

Reference yield:

2-chloro-propionic acid methyl ester (17639-93-9) + sodium 4-chloro-2-methyl-phenolate (52106-86-2) → methyl R-2-(4-chloro-2-methylphenoxy)propanoate (23844-56-6,2786-19-8)

Guidance literature:

tris-(3,6-dioxa-octyl)amine; In water; toluene;

Reference yield:

methyl R-2-(4-chloro-2-methylphenoxy)propanoate (23844-56-6,2786-19-8) → (R)-Mecoprop (16484-77-8,18221-59-5,7085-19-0) + (S)-mecoprop (25333-13-5,18221-59-5,7085-19-0)

Guidance literature:

With phosphate buffer; β‐cyclodextrin; at 37 ℃; for 4h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; bovine serum albumin (BSA);

DOI:10.1016/S0957-4166(00)82154-0

upstream raw materials:

2-chloro-propionic acid methyl ester

sodium 4-chloro-2-methyl-phenolate

Methyl 2-bromopropionate

2-methyl-4-chlorophenol

Downstream raw materials:

(R)-Mecoprop

(S)-mecoprop

(S)-mecoprop methyl ester

2-[4-chloro-2-methylphenoxy]propionic acid methyl ester

Refernces

• 1、 Seo, Yohan,Kim, Jinhwang,Chang, Jiwon,Kim, Seong Soon,Namkung, Wan,Kim, Ikyon. "Synthesis and biological evaluation of novel Ani9 derivatives as potent and selective ANO1 inhibitors". . p. 245 - 255. Retrieved 2018/10/24.