1-Naphthaleneethanol, 1,2,3,4-tetrahydro-

Base Information

• Chemical Name: 1-Naphthaleneethanol, 1,2,3,4-tetrahydro-
• CAS No.: 68480-12-6
• Deprecated CAS: 137847-82-6
• Molecular Formula: C12H16O
• Molecular Weight: 176.258
• European Community (EC) Number: 270-888-4
• NSC Number: 71475
• UNII: F093AWN8YQ
• DSSTox Substance ID: DTXSID40887413
• Nikkaji Number: J326.637K
• Wikidata: Q27277474
• Mol file: 68480-12-6.mol

Synonyms:68480-12-6;2-(1,2,3,4-tetrahydronaphthalen-1-yl)ethanol;1-Naphthaleneethanol, 1,2,3,4-tetrahydro-;1,2,3,4-Tetrahydronaphthalene-1-ethanol;1,2,3,4-Tetrahydro-1-naphthaleneethanol;UNII-F093AWN8YQ;F093AWN8YQ;2-(1,2,3,4-tetrahydronaphthalen-1-yl)ethan-1-ol;EINECS 270-888-4;NSC-71475;tetraline-ethanol;NSC71475;SCHEMBL5477158;DTXSID40887413;MFCD12828571;NSC 71475;AKOS013284231;1-Naphthaleneethanol,2,3,4-tetrahydro-;CS-0233852;EN300-136560;1,2,3,4 - tetrahydronaphthalene - 1 - ethanol;J-505289;Q27277474;Z1183459288

Chemical Property of 1-Naphthaleneethanol, 1,2,3,4-tetrahydro-

Chemical Property:

• Vapor Pressure: 0.000507mmHg at 25°C
• Boiling Point: 300.2°Cat760mmHg
• Flash Point: 131.7°C
• PSA: 20.23000
• Density: 1.028g/cm³
• LogP: 2.48890
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 176.120115130
• Heavy Atom Count: 13
• Complexity: 155

Purity/Quality:

99% ^*data from raw suppliers

2-(1,2,3,4-Tetrahydronaphthalen-1-yl)ethanol 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC(C2=CC=CC=C2C1)CCO

Technology Process of 1-Naphthaleneethanol, 1,2,3,4-tetrahydro-

There total 11 articles about 1-Naphthaleneethanol, 1,2,3,4-tetrahydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

ethyl (1,2,3,4-tetrahydrnaphthalen-5-yl)acetate (62741-60-0,170856-56-1) → 2-(1,2,3,4-tetrahydronaphthalen-1-yl)ethanol (68480-12-6)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃; for 2h;

Reference yield:

2-(3,4-dihydro-naphthalen-1-yl)-acetic acid ethyl ester (54125-45-0) → 2-(1,2,3,4-tetrahydronaphthalen-1-yl)ethanol (68480-12-6)

Guidance literature:

With lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; Multistep reaction;

Reference yield:

butan-1-ol (71-36-3) → 2-(1,2,3,4-tetrahydronaphthalen-1-yl)ethanol (68480-12-6)

Guidance literature:

With sodium; at 60 ℃; zuletzt bei 135-140grad;

DOI:10.1080/00377310209517656

upstream raw materials:

2-(5-phenylbutyl)oxirane

ethyl (1,2,3,4-tetrahydrnaphthalen-5-yl)acetate

2-(3,4-dihydro-naphthalen-1-yl)-acetic acid ethyl ester

butan-1-ol

Downstream raw materials:

2-naphthaleneethanol

1-Methylnaphthalene

1-ethylnapthelene

(R)-1-ethenyl-1-(4-methoxyphenyl)-1,2,3,4-tetrahydronaphthalene

Refernces

• 1、 -. "Sbstituted chroman derivatives, processes for their preparation and their use as antiinflammatory agents". . . Retrieved 2008/06/13.
• 2、 -. "Heterocyclic compounds for the treatment of CNS and cardiovascular disorders". . . Retrieved 2008/06/13.