N-(1-Naphthyl)Maleamic Acid

Base Information

• Chemical Name: N-(1-Naphthyl)Maleamic Acid
• CAS No.: 6973-77-9
• Molecular Formula: C₁₄H₁₁NO₃
• Molecular Weight: 241.246
• NSC Number: 41145,24013
• DSSTox Substance ID: DTXSID70364328
• Nikkaji Number: J800.953H
• Wikidata: Q82148221
• Mol file: 6973-77-9.mol

Synonyms:N-(1-Naphthyl)Maleamic Acid;6973-77-9;(2Z)-4-(1-naphthylamino)-4-oxobut-2-enoic acid;(Z)-4-(naphthalen-1-ylamino)-4-oxobut-2-enoic acid;MFCD00021446;(2Z)-3-[(naphthalen-1-yl)carbamoyl]prop-2-enoic acid;NSC24013;4-Chlorophenylzinciodide;n-1-naphthyl maleamic acid;N-1-Naphthyl maleamidic acid;SCHEMBL6892140;(2Z)-4-(naphthalen-1-ylamino)-4-oxobut-2-enoic acid;DTXSID70364328;NSC41145;NSC-24013;NSC-41145;STK279660;N-(alpha-NAPHTHYL)MALEAMIC ACID;AKOS000296096;N-(1-NAPHTHYL)-MALEAMIC ACID;LS-04437;3-(Naphthalen-1-ylcarbamoyl)-acrylic acid;(Z)-4-(1-naphthylamino)-4-oxo-2-butenoic acid;SR-01000404009;SR-01000404009-1;F0856-0439

Chemical Property of N-(1-Naphthyl)Maleamic Acid

Chemical Property:

• Vapor Pressure: 3.15E-12mmHg at 25°C
• Refractive Index: 1.706
• Boiling Point: 533.9 °C at 760 mmHg
• Flash Point: 276.7 °C
• PSA: 66.40000
• Density: 1.356 g/cm³
• LogP: 2.49210
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 241.07389321
• Heavy Atom Count: 18
• Complexity: 351

Purity/Quality:

99% ^*data from raw suppliers

(Z)-4-(Naphthalen-1-ylamino)-4-oxobut-2-enoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.
• Hazard Codes: R36/37/38:Irritating to eyes, respiratory system and skin.
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36:Wear suitable prot

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2NC(=O)C=CC(=O)O
• Isomeric SMILES: C1=CC=C2C(=C1)C=CC=C2NC(=O)/C=C\C(=O)O

Technology Process of N-(1-Naphthyl)Maleamic Acid

There total 2 articles about N-(1-Naphthyl)Maleamic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

maleic anhydride (108-31-6) + 1-amino-naphthalene (134-32-7) → N-(1-naphthyl)maleamic acid (119206-63-2,6973-77-9)

Guidance literature:

at 20 ℃;

DOI:10.3109/14756366.2015.1071808

Reference yield:

→ N-(1-naphthyl)maleamic acid (119206-63-2,6973-77-9)

Guidance literature:

Maleinsaeureanhydrid, α-Naphthylamin, k.Bzl.;

Reference yield: 70.0%

N-(1-naphthyl)maleamic acid (119206-63-2,6973-77-9) → N-(1-naphthalenyl)maleimide (3369-39-9)

Guidance literature:

With phosphorus pentaoxide; sulfuric acid; at 65 ℃; for 3h;

upstream raw materials:

maleic anhydride

1-amino-naphthalene

Downstream raw materials:

N-(1-naphthalenyl)maleimide

C₄₃H₂₇NO₃

Refernces

• 1、 Jia, Qianfa,Chen, Lei,Yang, Gongming,Wang, Jian,Wei, Jia,Du, Zhiyun. "DABCO-catalyzed [3+2] cycloaddition reactions of azomethine imines with N-aryl maleimides: Facile access to dinitrogen-fused heterocycles". supporting information. p. 7150 - 7153. Retrieved 2015/12/12.
• 2、 Hiran,Chaudhary, Jyoti,Meena, Suresh,Paliwal, Shiv Narayan. "AIBN initiated free radical homopolymerization of N-(1-naphthyl)maleimide and copolymerization with MMA: Synthesis and characterization". experimental part. p. 607 - 614. Retrieved 2009/07/18.