9-Chloro-9-phenyl-9H-xanthene

Base Information

• Chemical Name: 9-Chloro-9-phenyl-9H-xanthene
• CAS No.: 42506-03-6
• Molecular Formula: C19H13ClO
• Molecular Weight: 292.765
• Hs Code.: 2932999099
• European Community (EC) Number: 255-857-5
• UNII: 3DJX63N6JH
• DSSTox Substance ID: DTXSID00195288
• Nikkaji Number: J309.934B
• Wikidata: Q83068168
• Mol file: 42506-03-6.mol

Synonyms:9-Chloro-9-phenylxanthene;42506-03-6;9-Chloro-9-phenyl-9H-xanthene;Pixyl chloride;9H-Xanthene,9-chloro-9-phenyl-;3DJX63N6JH;EINECS 255-857-5;9-phenyl-9-chloroxanthen;9-Chloro-9-phenylxanthen;UNII-3DJX63N6JH;SCHEMBL3729918;9-PHENYLXANTHYL CHLORIDE;DTXSID00195288;9-Chloro-9-phenylxanthene, 97%;MFCD00010195;AKOS015916620;AS-58384;9H-XANTHENE, 9-CHLORO-9-PHENYL-;CS-0332330;FT-0760800;A930349

Chemical Property of 9-Chloro-9-phenyl-9H-xanthene

Chemical Property:

• Vapor Pressure: 7.54E-06mmHg at 25°C
• Melting Point: 102-106 °C(lit.)
• Refractive Index: 1.682
• Boiling Point: 387.1 °C at 760 mmHg
• Flash Point: 186.1 °C
• PSA: 9.23000
• Density: 1.3 g/cm³
• LogP: 5.32300
• Solubility.: chloroform: soluble25mg/mL, clear, yellow to orange
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 292.0654927
• Heavy Atom Count: 21
• Complexity: 341

Purity/Quality:

98%,99%, ^*data from raw suppliers

9-Chloro-9-phenylxanthene 97% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2(C3=CC=CC=C3OC4=CC=CC=C42)Cl
• Uses: 9-Chloro-9-phenylxanthene was used in the preparation of (1S,5S,6R,8S)-6-[(allyloxycarbonyl)oxy]-5-(trifluoroacetamido)-8-[9′-(9′-phenylxanthenyl)oxy]-2-oxabicyclo(3.2.1)octane.

Technology Process of 9-Chloro-9-phenyl-9H-xanthene

There total 9 articles about 9-Chloro-9-phenyl-9H-xanthene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

9-phenyl-9H-xanthen-9-ol (596-38-3) → pixyl chloride (42506-03-6)

Guidance literature:

With oxalyl dichloride; In dichloromethane; toluene; at 20 ℃; for 2h;

DOI:10.1081/NCN-200065966

Reference yield:

→ pixyl chloride (42506-03-6)

Guidance literature:

With air; Petroleum ether; at 50 - 60 ℃;

Reference yield:

9?phenylxanthen?9?ylium perchlorate (6631-16-9) → pixyl chloride (42506-03-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 1,) NaH / 1.) THF, 2) THF, 1 h, room t.

2: 96 percent / HCl gas / benzene / 5 h / Heating; reactions between var. conditions

3: acetyl chloride / diethyl ether

With hydrogenchloride; sodium hydride; acetyl chloride; In diethyl ether; benzene;

DOI:10.1039/P19880002271

upstream raw materials:

9-phenyl-9H-xanthen-9-ol

acetyl chloride

9?phenylxanthen?9?ylium perchlorate

C₄₄H₃₀O₃

Downstream raw materials:

9-(hydroxyethoxymethyl)-2-N-(9-phenylxanthen-9-yl)-guanine

N²-(anthracen-9-ylmethyl)-5'-O-(9-phenylxanthen-9-yl)-2'-deoxyguanosine

5'-O-(tert-butyldiphenylsilyl)-2'.3'-bis-O-(9-phenylxanthen-9-yl)uridine

6-N-(m-chlorobenzoyl)-5'-O-pixyl-2'-deoxyadenosine

Refernces

• 1、 Day, Robert T.,Williams, Dean,Soriano, Priscilla,Sanghvi, Yogesh S.. "Large-scale synthesis of 5′-O-pixyl protected 2′- deoxynucleosides useful for oligonucleotide synthesis". . p. 1135 - 1138. Retrieved 2008/02/01.