1-Chloro-3-methoxypropane

Base Information

• Chemical Name: 1-Chloro-3-methoxypropane
• CAS No.: 36215-07-3
• Molecular Formula: C4H9ClO
• Molecular Weight: 108.568
• Hs Code.: 2909199090
• European Community (EC) Number: 252-919-3
• DSSTox Substance ID: DTXSID70189770
• Nikkaji Number: J319.611I
• Wikidata: Q72453382
• Mol file: 36215-07-3.mol

Synonyms:1-Chloro-3-methoxypropane;36215-07-3;3-Chloropropyl Methyl Ether;1-chloro-3-methoxy-Propane;Propane, 1-chloro-3-methoxy-;EINECS 252-919-3;3-Methoxypropyl Chloride;3-chloro-methoxy propane;1-chlor-3-methoxypropane;3-methoxy-1-chloropropane;methyl 3-chloropropyl ether;1 -chloro-3-methoxypropane;1-Chloro-3-methoxypropane #;SCHEMBL600700;methyl (3-chloropropyl) ether;DTXSID70189770;AMY25654;MFCD05663419;AKOS000169602;GS-3231;SB36831;C2055;FT-0639308;EN300-42679;H11766;A823166

Chemical Property of 1-Chloro-3-methoxypropane

Chemical Property:

• Vapor Pressure: 44mmHg at 25°C
• Melting Point: NA
• Refractive Index: 1.399
• Boiling Point: 99.4 °C at 760 mmHg
• Flash Point: 27.9 °C
• PSA: 9.23000
• Density: 0.966 g/cm³
• LogP: 1.26170
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly)
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 108.0341926
• Heavy Atom Count: 6
• Complexity: 23.5

Purity/Quality:

99.0% min ^*data from raw suppliers

1-Chloro-3-methoxypropane ^*data from reagent suppliers

Safty Information:

• Statements: 11
• Safety Statements: 9-16-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCCCCl
• Uses: 1-Chloro-3-methoxypropane (cas# 36215-07-3) is a compound useful in organic synthesis.

Technology Process of 1-Chloro-3-methoxypropane

There total 11 articles about 1-Chloro-3-methoxypropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

methoxypropanol (1589-49-7) → 1-Chloro-3-methoxypropane (36215-07-3)

Guidance literature:

With pyridine; thionyl chloride; at 10 - 65 ℃; for 3h;

Reference yield: 47.0%

methanol (67-56-1) + 1.3-chlorobromopropane (109-70-6) → 1-Chloro-3-methoxypropane (36215-07-3)

Guidance literature:

With sodium methylate; at 20 ℃;

DOI:10.1002/ejic.200390020

Reference yield:

methanol (67-56-1) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → 1-Chloro-3-methoxypropane (36215-07-3)

Guidance literature:

With tin incorporated into nano zeolite beta framework; In acetone; at 60 ℃; for 24h; Reagent/catalyst; regioselective reaction; Catalytic behavior;

DOI:10.1016/j.apcata.2019.03.009

upstream raw materials:

methoxypropanol

ethene

chloromethyl methyl ether

sodium methylate

Downstream raw materials:

1-iodo-3-methoxypropane

1-(3-methoxypropoxy)-2-nitrobenzene

4-bromo-2-(3-methoxypropoxy)-1-methylbenzene

1-bromo-3-(3-methoxypropoxy)benzene

Refernces

• 1、 Parulkar, Aamena,Spanos, Alexander P.,Deshpande, Nitish,Brunelli, Nicholas A.. "Synthesis and catalytic testing of Lewis acidic nano zeolite Beta for epoxide ring opening with alcohols". . p. 28 - 34. Retrieved 2019/03/28.
• 2、 -. "Spirocyclic Cyclohexane Compounds". Page/Page column 12. . Retrieved 2010/03/31.