Tyrocidine A

Base Information Edit

Chemical Name:Tyrocidine A
CAS No.:1481-70-5
Deprecated CAS:1406-13-9,11005-75-7
Molecular Formula:C66H87 N13 O13
Molecular Weight:1270.5
Hs Code.:
European Community (EC) Number:232-375-3
UNII:V134656H89
ChEMBL ID:CHEMBL408504
DSSTox Substance ID:DTXSID40163885
Metabolomics Workbench ID:54093
Nikkaji Number:J14.834B
Wikidata:Q3546357
Mol file:1481-70-5.mol

Synonyms:Brevicidin;Rapicidin;Tyrocidine;Tyrocidines

Suppliers and Price of Tyrocidine A

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of Tyrocidine A Edit

Chemical Property:

PSA：414.64000
LogP:4.61050
XLogP3:2.8
Hydrogen Bond Donor Count:13
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:19
Exact Mass:1269.65462988
Heavy Atom Count:92
Complexity:2510

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements:Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When heated to deco"> x and HCl." target="_blank">Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When heated to deco

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC1C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN)C(C)C)CC3=CC=C(C=C3)O)CCC(=O)N)CC(=O)N)CC4=CC=CC=C4)CC5=CC=CC=C5)CC6=CC=CC=C6
Isomeric SMILES:CC(C)C[C@H]1C(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCN)C(C)C)CC3=CC=C(C=C3)O)CCC(=O)N)CC(=O)N)CC4=CC=CC=C4)CC5=CC=CC=C5)CC6=CC=CC=C6

Technology Process of Tyrocidine A

There total 13 articles about Tyrocidine A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.9%

: D-Phe-Pro-Phe-D-Phe-Asn-Gln-Tyr-Val-Orn-Leu-OH

: 1481-70-5
Tyrocidine A

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; for 6h;
DOI:10.1039/c7cc00506g

Reference yield:

: 1481-70-5
Tyrocidine A

Guidance literature:: 4-sulfamylbutyryl AM resin-bound BocNH-DPhe-Pro-Phe-DPhe-Asn-Gln-Tyr-Val-Orn(Boc)-Leu; With aluminum oxide; iodoacetonitrile; N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 24h;

With chlorotriisopropylsilane; trifluoroacetic acid; phenol; water; at 20 ℃; for 2h;

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 24h; Further stages.;
DOI:10.1016/j.bmc.2007.08.007