Octanoic acid hydrazide

Base Information

• Chemical Name: Octanoic acid hydrazide
• CAS No.: 6304-39-8
• Molecular Formula: C8H18 N2 O
• Molecular Weight: 158.244
• Hs Code.: 29280000
• European Community (EC) Number: 228-612-5
• NSC Number: 227236,42947
• UNII: WQ7QGY5XUT
• DSSTox Substance ID: DTXSID4064218
• Nikkaji Number: J26.740F
• Wikidata: Q72497413
• Mol file: 6304-39-8.mol

Synonyms:caprylic hydrazide;octanoic acid hydrazide;octanoylhydrazide

Chemical Property of Octanoic acid hydrazide

Chemical Property:

• Appearance/Colour: White Flake Crystal
• Vapor Pressure: 0.00103mmHg at 25°C
• Melting Point: 87-89 ºC
• Refractive Index: 1.456
• Boiling Point: 301.8 °C at 760 mmHg
• PKA: 13.62±0.18(Predicted)
• Flash Point: 136.3 °C
• PSA: 55.12000
• Density: 0.929 g/cm³
• LogP: 2.42800
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• Solubility.: soluble in Methanol
• XLogP3: 1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 158.141913202
• Heavy Atom Count: 11
• Complexity: 104

Purity/Quality:

98%,99%, ^*data from raw suppliers

n-Octanohydrazide >97.0%(GC)(T) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn,Xi
• Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCC(=O)NN

Technology Process of Octanoic acid hydrazide

There total 6 articles about Octanoic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

Octanoic acid (124-07-2) → caprylic hydrazide (6304-39-8)

Guidance literature:

With Novozym 435 (Candida antarctica lipase B on Lewatit E); hydrazine; In tert-butyl alcohol; at 40 ℃; for 20h; Enzymatic reaction;

DOI:10.1007/s007060070086

Reference yield: 33.0%

octanoic acid ethyl ester (106-32-1) → caprylic hydrazide (6304-39-8)

Guidance literature:

With hydrazine hydrate; In ethanol; at 120 ℃; for 0.283333h; Microwave irradiation;

DOI:10.3390/molecules26144204

Reference yield:

methyl octanate (111-11-5) → caprylic hydrazide (6304-39-8)

Guidance literature:

With hydrazine;

upstream raw materials:

octanoic acid ethyl ester

methyl octanate

Octanoic acid

N'-[benz-(E)-ylidene]octanehydrazide

Downstream raw materials:

1-(pyrrolidin-1-yl)octan-1-one

Octanoic acid

octanoic acid (1,3-dioxo-1,3-dihydro-isoindol-2-yl)-amide

Octanoic acid N'-[(E)-3-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-{(2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-[(E)-3-(N'-octanoyl-hydrazino)-3-oxo-propenyl]-tetrahydro-pyran-2-yloxy}-tetrahydro-pyran-2-yl)-acryloyl]-hydrazide

Refernces

• 1、 Akhgar, Mohammad Reza,Ghazanfari, Dadkhoda,Ghodratbeigi, Mohsen,Shirmohammadi, Mahdi,Souzangarzadeh, Saeid. "Microwave irradiated synthesis of Schiff bases of 4-(arylideneamino)-5-alkyl-2,4-dihydro-1,2,4-triazole-3-thione containing 1,2,4-triazole segment". . p. 1805 - 1813. Retrieved 2022/01/08.
• 2、 De Azevedo, Ricardo Alexandre,Ferreira, Adilson Kleber,Jorge, Salomo Dria,Palace-Berl, Fanny,Pasqualoto, Kerly Fernanda Mesquita,Silva, Marcelo Nunes,Tavares, Leoberto Costa,Teixeira, Sarah Fernandes,Zingales, Bianca,Zorzi, Rodrigo Rocha. "Designing and exploring active N′-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against three Trypanosoma cruzi strains more prevalent in Chagas disease patients". . p. 330 - 339. Retrieved 2015/04/27.