Vicenin -1

Base Information

• Chemical Name: Vicenin -1
• CAS No.: 35927-38-9
• Molecular Formula: C26H28O14
• Molecular Weight: 564.5
• Mol file: 35927-38-9.mol

Synonyms:

Chemical Property of Vicenin -1

Chemical Property:

• Melting Point: 230 °C (decomp)
• Boiling Point: 935.0±65.0 °C(Predicted)
• PKA: 5.70±0.40(Predicted)
• PSA: 250.97000
• Density: 1.766±0.06 g/cm3(Predicted)
• LogP: -1.75430

Purity/Quality:

99%, ^*data from raw suppliers

Vicenin-1 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Vicenin -1

There total 3 articles about Vicenin -1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

5,7,4'-triacetoxy-6-C-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-8-C-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)flavone (64065-70-9) → 6-(C-β-D-xylopyranosyl)-8-(C-β-D-glucopyranosyl)-4',5,7-trihydroxyflavone (35927-38-9)

Guidance literature:

5,7,4'-triacetoxy-6-C-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-8-C-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)flavone; With sodium methylate; In methanol; at 25 ℃;

In methanol;

DOI:10.1039/c0ob00011f

Reference yield: 31.0%

6-(C-β-D-glucopyranosyl)-8-(C-β-D-xylopyranosyl)-4',5,7-trihydroxyflavone → 6-(C-β-D-xylopyranosyl)-8-(C-β-D-glucopyranosyl)-4',5,7-trihydroxyflavone (35927-38-9)

Guidance literature:

With hydrogenchloride; In water; for 2h; Reflux;

DOI:10.1016/j.carres.2010.04.001

Reference yield:

C54H54O14 + acetic anhydride (108-24-7) → 6-(C-β-D-xylopyranosyl)-8-(C-β-D-glucopyranosyl)-4',5,7-trihydroxyflavone (35927-38-9) + 6-(C-β-D-glucopyranosyl)-8-(C-β-D-xylopyranosyl)-4',5,7-trihydroxyflavone

Guidance literature:

C₅₄H₅₄O₁₄; In methanol; Reflux;

With palladium 10% on activated carbon; hydrogen;

acetic anhydride; Further stages;

DOI:10.1016/j.carres.2010.04.001

upstream raw materials:

acetic anhydride

5,7,4'-triacetoxy-6-C-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-8-C-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)flavone

Refernces

• 1、 Shie, Jiun-Jie,Chen, Chih-An,Lin, Chih-Chien,Ku, Angela Fay,Cheng, Ting-Jen R.,Fang, Jim-Min,Wong, Chi-Huey. "Regioselective synthesis of di-C-glycosylflavones possessing anti-inflammation activities". experimental part. p. 4451 - 4462. Retrieved 2010/11/05.