BIS(DIETHYLAMINO)PHENYLPHOSPHINE 97

Base Information

• Chemical Name: BIS(DIETHYLAMINO)PHENYLPHOSPHINE 97
• CAS No.: 1636-14-2
• Molecular Formula: C14H25N2P
• Molecular Weight: 252.34
• Mol file: 1636-14-2.mol

Synonyms:Bis(diethylamino)phenylphosphine;N,N,N',N'-Tetraethyl-P-phenylphosphonous diamide;N,N,N'N'-Tetraethylphenylphosphonousdiamide;NSC 244337;Phenylphosphonous tetraethyldiamide;

Chemical Property of BIS(DIETHYLAMINO)PHENYLPHOSPHINE 97

Chemical Property:

• Vapor Pressure: 0.000129mmHg at 25°C
• Boiling Point: 334.4 °C at 760 mmHg
• PKA: 6.94±0.70(Predicted)
• Flash Point: 156 °C
• PSA: 20.07000
• Density: 0.971 g/mL at 25 °C(lit.)
• LogP: 3.30740

Purity/Quality:

98%,99%, ^*data from raw suppliers

Bis(diethylamino)phenylphosphine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Electron-withdrawing cocatalyst in rhodium catalyzed hydroformylation reactions. Ligand precatalyst for Heck coupling reactions. Reactant for: Preparation of palladium chiral P-N ligand complexes for regio- and stereo-selective dimerization reactions. Preparation of palladium tautomeric ferrocenylphosphinites as catalysts for Suzuki-Miyaura coupling. Trimethylsilyl halide-promoted Michaelis-Arbuzov rearrangement of phosphinites and phosphites. Electron-withdrawing cocatalyst in rhodium catalyzed hydroformylation reactionsLigand precatalyst for Heck coupling reactionsReactant for: Preparation of palladium chiral P-N ligand complexes for regio- and stereo-selective dimerization reactionsPreparation of palladium tautomeric ferrocenylphosphinites as catalysts for Suzuki-Miyaura couplingTrimethylsilyl halide-promoted Michaelis-Arbuzov rearrangement of phosphinites and phosphites

Technology Process of BIS(DIETHYLAMINO)PHENYLPHOSPHINE 97

There total 8 articles about BIS(DIETHYLAMINO)PHENYLPHOSPHINE 97 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

Dichlorophenylphosphine (644-97-3) + diethylamine (109-89-7) → bis(diethylamino)phenylphosphine (1636-14-2)

Guidance literature:

In diethyl ether; at 0 - 20 ℃;

DOI:10.1021/om5005989

Reference yield: 53.0%

(diethylamino)phenylchlorophosphine (4073-31-8) + 1,4-bis(bromomagnesium)butane (23708-47-6) → 1,4-Butandiylbis<(diethylamino)phenylphosphan> (82159-38-4) + bis(diethylamino)phenylphosphine (1636-14-2)

Guidance literature:

In tetrahydrofuran; 1,4-dioxane; pyridine; for 3h; Ambient temperature;

Reference yield:

diethylamine (109-89-7) + phenyldibromophosphine (1073-47-8) → bis(diethylamino)phenylphosphine (1636-14-2)

Guidance literature:

In toluene; at 0 - 20 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

DOI:10.1055/s-0033-1339548

upstream raw materials:

Dichlorophenylphosphine

diethylamine

N,N-diethyl-1,1,1-trimethylsilanamine

(diethylamino)phenylchlorophosphine

Downstream raw materials:

phenylphosphonous acid bis-(3-methyl-3H-benzothiazol-2-ylideneamide)

2-phenyl-1,3,2-oxazaphospholidine

(diethylamino)phenylchlorophosphine

2-phenyl-3-methyl-1,3,2-oxazaphospholidine

Refernces

• 1、 Bigler, Raphael,Otth, Elisabeth,Mezzetti, Antonio. "Chiral macrocyclic N2P2 ligands and Iron(II): A marriage of interest". supporting information. p. 4086 - 4099. Retrieved 2014/11/26.
• 2、 Wang, Lili,Zhang, Lujun,Shi, Hanyu,Duan, Zheng,Mathey, Fran?ois. "An unconventional synthesis of dibromophosphines". supporting information. p. 2006 - 2008. Retrieved 2013/09/24.