6-Azabicyclo[3.1.0]hexane

Base Information Edit

Chemical Name:6-Azabicyclo[3.1.0]hexane
CAS No.:285-63-2
Molecular Formula:C5H9 N
Molecular Weight:83.1332
Hs Code.:
European Community (EC) Number:878-433-7
DSSTox Substance ID:DTXSID70595150
Nikkaji Number:J2.485.304G
Mol file:285-63-2.mol

Synonyms:6-azabicyclo[3.1.0]hexane;Cyclopentenimine;285-63-2;DTXSID70595150;MFCD11858223;AKOS006221001;AT21516;CS-0249559;EN300-43894

Suppliers and Price of 6-Azabicyclo[3.1.0]hexane

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Cyclopentenimine
250mg
$ 165.00

Total 1 raw suppliers

Chemical Property of 6-Azabicyclo[3.1.0]hexane Edit

Chemical Property:

PSA：21.94000
LogP:0.83950
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:83.073499291
Heavy Atom Count:6
Complexity:62.3

Purity/Quality:

99% ^*data from raw suppliers

Cyclopentenimine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2C(C1)N2
Uses Cyclopentenimine is used in the novel synthesis of Tamiflu. as well as the preparation of aziridines.

Technology Process of 6-Azabicyclo[3.1.0]hexane

There total 16 articles about 6-Azabicyclo[3.1.0]hexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: (+/-)-trans-1-azido-2-iodocyclopentane

: 285-63-2
6-azabicyclo<3.1.0>hexane

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; at 0 - 20 ℃;
DOI:10.1080/10426501003773787

Reference yield: 70.0%

: (+/-)-trans-1-azido-2-iodocyclopentane

: 285-63-2
6-azabicyclo<3.1.0>hexane

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; 1.) 0 deg C, 30 min; 2.) up to RT, 12 h;
DOI:10.1002/hlca.19930760719

Reference yield:

: 285-67-6
Cyclopentene oxide

: 285-63-2
6-azabicyclo<3.1.0>hexane

Guidance literature:: Multi-step reaction with 3 steps

1: aq. NH₄OH / 140 °C / 15200 Torr

2: ClSO₃H / CCl₄ / 60 °C

3: aq. NaOH

With chlorosulfonic acid; ammonium hydroxide; sodium hydroxide; In tetrachloromethane;