3-(Tetradecyloxy)propylamine

Base Information

• Chemical Name: 3-(Tetradecyloxy)propylamine
• CAS No.: 7617-82-5
• Molecular Formula: C₁₇H₃₇NO
• Molecular Weight: 271.487
• European Community (EC) Number: 231-531-8
• UNII: XBU69CCN6Y
• DSSTox Substance ID: DTXSID5064752
• Nikkaji Number: J116.195D
• Wikidata: Q81991802
• ChEMBL ID: CHEMBL2036097
• Mol file: 7617-82-5.mol

Synonyms:3-(Tetradecyloxy)propylamine;7617-82-5;3-tetradecoxypropan-1-amine;Propylamine, 3-(tetradecyloxy)-;1-Propanamine, 3-(tetradecyloxy)-;EINECS 231-531-8;3-MYRISTYLOXY PROPYLAMINE;XBU69CCN6Y;SCHEMBL116909;Tetradecyl 3-aminopropyl ether;C17H37NO;CHEMBL2036097;DTXSID5064752;3-(tetradecyloxy)propan-1-amine;3-(Tetradecyloxy)-1-propanamine;C17-H37-N-O;FT-0613893

Chemical Property of 3-(Tetradecyloxy)propylamine

Chemical Property:

• Vapor Pressure: 1.35E-05mmHg at 25°C
• Boiling Point: 367.6°C at 760 mmHg
• Flash Point: 149.7°C
• PSA: 35.25000
• Density: 0.85g/cm³
• LogP: 5.75320
• XLogP3: 6.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 16
• Exact Mass: 271.287514804
• Heavy Atom Count: 19
• Complexity: 150

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCOCCCN

Technology Process of 3-(Tetradecyloxy)propylamine

There total 3 articles about 3-(Tetradecyloxy)propylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

1-(3-azidopropoxy)tetradecane (1380680-80-7) → tetradecyloxypropyl amine (7617-82-5)

Guidance literature:

1-(3-azidopropoxy)tetradecane; With triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 0.166667h;

With water; In tetrahydrofuran; at 20 ℃; for 28h;

DOI:10.1016/j.bmc.2012.03.065

Reference yield:

1-Bromotetradecane (112-71-0) → tetradecyloxypropyl amine (7617-82-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide; oil / 0.17 h / 0 - 20 °C

1.2: 4 h / 95 °C

2.1: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 3 h / 90 °C

3.1: triphenylphosphine / tetrahydrofuran / 0.17 h / 20 °C

3.2: 28 h / 20 °C

With diphenyl phosphoryl azide; sodium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide; oil;

DOI:10.1016/j.bmc.2012.03.065

Reference yield:

3-tetradecyloxy-1-propanol (81749-13-5) → tetradecyloxypropyl amine (7617-82-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 3 h / 90 °C

2.1: triphenylphosphine / tetrahydrofuran / 0.17 h / 20 °C

2.2: 28 h / 20 °C

With diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2012.03.065

upstream raw materials:

1-(3-azidopropoxy)tetradecane

1-Bromotetradecane

3-tetradecyloxy-1-propanol

Refernces