2-benzyl-1,3-diphenylpropan-2-ol

Base Information

• Chemical Name: 2-benzyl-1,3-diphenylpropan-2-ol
• CAS No.: 6712-97-6
• Molecular Formula: C22H22O
• Molecular Weight: 302.416
• Mol file: 6712-97-6.mol

Synonyms:

Chemical Property of 2-benzyl-1,3-diphenylpropan-2-ol

Chemical Property:

• Vapor Pressure: 2.32E-08mmHg at 25°C
• Boiling Point: 435.7°C at 760 mmHg
• Flash Point: 160.8°C
• Density: 1.102g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-benzyl-1,3-diphenylpropan-2-ol

There total 23 articles about 2-benzyl-1,3-diphenylpropan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

benzylmagnesium chloride (6921-34-2) + 1,3-Diphenylpropanone (102-04-5) → tribenzylcarbinol (6712-97-6)

Guidance literature:

In diethyl ether; for 12h;

DOI:10.1021/ja962545s

Reference yield: 81.0%

benzyl bromide (100-39-0) + carbonic acid dimethyl ester (616-38-6) → tribenzylcarbinol (6712-97-6)

Guidance literature:

With samarium; copper(l) iodide; In tetrahydrofuran; at 20 ℃; for 10h; Reagent/catalyst; Inert atmosphere;

DOI:10.1039/d1cc00965f

Reference yield: 79.0%

benzyl chloride (100-44-7) + carbonic acid dimethyl ester (616-38-6) → tribenzylcarbinol (6712-97-6)

Guidance literature:

benzyl chloride; With magnesium; In diethyl ether; for 0.75h; Reflux; Inert atmosphere;

carbonic acid dimethyl ester; In diethyl ether; at 20 ℃; for 20h; Inert atmosphere;

DOI:10.1021/ja2081907

upstream raw materials:

chloroformic acid ethyl ester

benzylmagnesium chloride

benzyl chloride

Diethyl carbonate

Downstream raw materials:

2-benzyl-1,3-diphenyl-1-propene

1,3-di(cyclohexa-1,4-dienyl)-2-(cyclohexa-1,4-dienylmethyl)propan-2-ol

2-benzyl-2-bromo-1,3-diphenyl-propane

2-benzyl-1,3-diphenyl-propane

Refernces

• 1、 Mori, Yasuyuki,Shigeno, Chieko,Luo, Ying,Chan, Bun,Onodera, Gen,Kimura, Masanari. "Ni-Catalyzed Formal Carbonyl-Ene Reaction of Terminal Alkenes via Carbon Dioxide Insertion". supporting information. p. 742 - 746. Retrieved 2018/03/26.
• 2、 Shokri, Alireza,Schmidt, Jacob,Wang, Xue-Bin,Kass, Steven R.. "Hydrogen bonded arrays: The power of multiple hydrogen bonds". experimental part. p. 2094 - 2099. Retrieved 2012/03/12.