Efaroxan hydrochloride

Base Information

• Chemical Name: Efaroxan hydrochloride
• CAS No.: 89197-00-2
• Molecular Formula: C13H17ClN2O
• Molecular Weight: 252.74
• Hs Code.: 2934999090
• European Community (EC) Number: 635-875-3
• NSC Number: 759562
• DSSTox Substance ID: DTXSID00474686
• ChEMBL ID: CHEMBL539313
• Mol file: 89197-00-2.mol

Synonyms:2-((2-ethyl-2,3-dihydrobenzofuran-2-yl))-2-imidazoline;efaroxan;efaroxan hydrochloride

Chemical Property of Efaroxan hydrochloride

Chemical Property:

• Boiling Point: 387 °C at 760 mmHg
• Flash Point: 187.9 °C
• PSA: 33.62000
• LogP: 2.33840
• Storage Temp.: Store at RT
• Solubility.: H2O: 300 mg/mL
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 252.1029409
• Heavy Atom Count: 17
• Complexity: 302

Purity/Quality:

98%,99%, ^*data from raw suppliers

Efaroxan hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25
• Safety Statements: 7-35-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1(CC2=CC=CC=C2O1)C3=NCCN3.Cl
• Description: Efaroxan HCl (89197-00-2) is a selective α2-adrenergic receptor antagonist1 (selectivity ratio of α2/α1 = 724)4 and imidazoline receptor antagonist2. Induces release of insulin in the rat insulinoma cell line RIN-5AH by interaction with ATP-sensitive potassium channels independently from imidazoline I1 or I2 receptors.3 Efaroxan HCl increases resting plasma insulin levels and markedly potentiates the rise in insulin levels produced by adrenaline in the rat.4
• Uses: Efaroxan Hydrochloride is a potent α2-AR adrenoceptor antagonist.