Bis(2-(dimethylamino)ethyl) succinate

Base Information

• Chemical Name: Bis(2-(dimethylamino)ethyl) succinate
• CAS No.: 19249-04-8
• Molecular Formula: C12H24 N2 O4
• Molecular Weight: 260.334
• European Community (EC) Number: 242-917-0
• DSSTox Substance ID: DTXSID50172842
• Nikkaji Number: J242.753B
• Wikidata: Q83042931
• Mol file: 19249-04-8.mol

Synonyms:Bis(2-(dimethylamino)ethyl) succinate;19249-04-8;bis[2-(dimethylamino)ethyl] succinate;bis[2-(dimethylamino)ethyl] butanedioate;EINECS 242-917-0;SCHEMBL3038090;DTXSID50172842;2-(dimethylamino) ethyl succinate;bis(2-dimethylaminoethyl) succinate;Bis(2-dimethylaminoethyl)butanedioate;Bis-(beta-dimethylaminoethyl)succinate;AKOS002860535;Succinic acid bis[2-(dimethylamino)ethyl] ester;A1-01701;Butanedioic acid, bis(2-(dimethylamino)ethyl) ester;1,4-BIS[2-(DIMETHYLAMINO)ETHYL] BUTANEDIOATE

Chemical Property of Bis(2-(dimethylamino)ethyl) succinate

Chemical Property:

• Vapor Pressure: 0.000299mmHg at 25°C
• Boiling Point: 321.4°Cat760mmHg
• Flash Point: 148.2°C
• PSA: 59.08000
• Density: 1.049g/cm³
• LogP: -0.02380
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 11
• Exact Mass: 260.17360725
• Heavy Atom Count: 18
• Complexity: 229

Purity/Quality:

99% ^*data from raw suppliers

Bis(2-?(dimethylamino)?ethyl)Succinate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCOC(=O)CCC(=O)OCCN(C)C
• Uses: Bis(2-?(dimethylamino)?ethyl) Succinate is a potential ligand which may act as an agonist/antagonist to nicotine.

Technology Process of Bis(2-(dimethylamino)ethyl) succinate

There total 6 articles about Bis(2-(dimethylamino)ethyl) succinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(N,N-dimethylamino)ethanol (108-01-0) + succinic acid diethyl ester (123-25-1) → bis-dimethylaminoethylsuccinate (19249-04-8)

Guidance literature:

With sodium;

DOI:10.1021/ja01177a535

Reference yield:

2-(N,N-dimethylamino)ethanol (108-01-0) + Dimethyl succinate (106-65-0) → bis-dimethylaminoethylsuccinate (19249-04-8)

Guidance literature:

With sodium;

DOI:10.1021/ja01177a535

Reference yield:

succinic acid anhydride (108-30-5) + 2-(dimethylamino)ethyl chloride (107-99-3) → bis-dimethylaminoethylsuccinate (19249-04-8)

Guidance literature:

With sodium N,N-dimethylethanolamine; In toluene;

upstream raw materials:

succinic acid anhydride

sodium N,N-dimethylethanolamine

2-(dimethylamino)ethyl chloride

2-(N,N-dimethylamino)ethanol

Downstream raw materials:

Ascuron

succinylcholine chloride

succinic acid bis-{2-[(4-bromo-phenacyl)-dimethyl-ammonio]-ethyl ester}; dibromide

succinic acid bis-[2-(ethyl-dimethyl-ammonio)-ethyl ester]; dibromide

Refernces