3,4-Dichloro-N-(1-Methylbutyl)benza-Mide

Base Information

• Chemical Name: 3,4-Dichloro-N-(1-Methylbutyl)benza-Mide
• CAS No.: 7497-07-6
• Molecular Formula: C12H15Cl2NO
• Molecular Weight: 260.1596
• Hs Code.: 29242990
• Mol file: 7497-07-6.mol

Synonyms:

Chemical Property of 3,4-Dichloro-N-(1-Methylbutyl)benza-Mide

Chemical Property:

• Vapor Pressure: 3.52E-05mmHg at 25°C
• Boiling Point: 353.7°C at 760 mmHg
• PKA: 13.38±0.46(Predicted)
• Flash Point: 167.7°C
• PSA: 29.10000
• Density: 1.182g/cm³
• LogP: 4.30270
• Storage Temp.: room temp
• Solubility.: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Purity/Quality:

98% min ^*data from raw suppliers

NSC 405020 ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Description: NSC-405020 (7497-07-6) is a membrane type-1 matrix metalloproteinase (MMP14 or MT1-MMP) inhibitor that prevents homodimerization and inhibits MMP14’s protumorigenic activity?in vivo. (IC50?> 100 μM). Inhibition is via interaction with the hemopexin domain (PEX) of MMP14. NSC-405020 does not interfere with the catalytic activity of MT1-MMP or MMP-2.? Suppresses bone erosion in a c-Fos-deficient mouse model.2?Decreases arsenic-mediated invasion of human squamous cell carcinoma HSC5 cells.3
• Uses: NSC 405020 is a novel, selective, and noncatalytic membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor that directly interacts with the homopexin (PEX) domain of MT1-MMP.

Technology Process of 3,4-Dichloro-N-(1-Methylbutyl)benza-Mide

There total 1 articles about 3,4-Dichloro-N-(1-Methylbutyl)benza-Mide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ NSC 405020 (7497-07-6)

Guidance literature:

3,4-Dichlorbenzoylchlorid, entspr.Amin, sd.Benzol;

Refernces