2-(6-CHLOROHEXYLOXY)TETRAHYDRO-2H-PYRAN&

Base Information

• Chemical Name: 2-(6-CHLOROHEXYLOXY)TETRAHYDRO-2H-PYRAN&
• CAS No.: 2009-84-9
• Molecular Formula: C11H21 Cl O2
• Molecular Weight: 220.74
• Hs Code.: 2932999099
• Mol file: 2009-84-9.mol

Synonyms:Pyran,2-[(6-chlorohexyl)oxy]tetrahydro- (7CI); 1-Tetrahydropyranyloxy-6-chlorohexane;2-(6-Chlorohexyloxy)tetrahydro-2H-pyran; 2-(6-Chlorohexyloxy)tetrahydropyran;6-(Tetrahydropyranyloxy)hexyl chloride; 6-Chloro-1-hexyl 2-tetrahydropyranylether; NSC 314555

Chemical Property of 2-(6-CHLOROHEXYLOXY)TETRAHYDRO-2H-PYRAN&

Chemical Property:

• Vapor Pressure: 0.00181mmHg at 25°C
• Refractive Index: n20/D 1.462(lit.)
• Boiling Point: 302.1°Cat760mmHg
• Flash Point: 97.3°C
• PSA: 18.46000
• Density: 1.01g/cm³
• LogP: 3.32880

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(6-Chlorohexyloxy)tetrahydro-2H-pyran 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-(6-Chlorohexyloxy)tetrahydro-2H-pyran may be used in the synthesis of 2-(6-isothiocyanatohexyloxy)-tetrahydro-2H-pyran.

Technology Process of 2-(6-CHLOROHEXYLOXY)TETRAHYDRO-2H-PYRAN&

There total 4 articles about 2-(6-CHLOROHEXYLOXY)TETRAHYDRO-2H-PYRAN& which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,4-dihydro-2H-pyran (110-87-2) + 6-chloro-1-hexanol (2009-83-8) → (chloro-6' hexyloxy)-2 tetrahydropyranne (2009-84-9)

Guidance literature:

With pyridinium p-toluenesulfonate; In dichloromethane; at 21 ℃; for 18h;

DOI:10.1016/j.steroids.2008.04.009

Reference yield: 74.0%

3,4-dihydro-2H-pyran (110-87-2) → (chloro-6' hexyloxy)-2 tetrahydropyranne (2009-84-9)

Guidance literature:

6-chloro-1-hexanol; With toluene-4-sulfonic acid; In dichloromethane; for 0.5h;

3,4-dihydro-2H-pyran; In dichloromethane; at 20 ℃; for 15.5h;

Reference yield:

→ (chloro-6' hexyloxy)-2 tetrahydropyranne (2009-84-9) + oct-7-yn-1-ol (871-91-0)

Guidance literature:

upstream raw materials:

3,4-dihydro-2H-pyran

6-chloro-1-hexanol

Downstream raw materials:

1-(3,5-Di-tert-butyl)-phenyl-1,7-heptandiol

2-<7-hydroxy-7-(3,5-dimethoxyphenyl)heptyloxy>tetrahydropyran

1-(2-Tetrahydropyranyloxy)-7-octyne

2-[(6-bromohexyl)oxy]tetrahydro-2H-pyran

Refernces

• 1、 -. "Preparation method of 2-(6-chlorohexyloxy) tetrahydro-2H-pyran". Paragraph 0038-0063. . Retrieved 2021/01/12.
• 2、 -. "Process synthesis method for fatty alcohol hydroxyl protection by adopting micro-reactor". Paragraph 0030-0079. . Retrieved 2021/01/11.